Dyląg-Trojanowska Katarzyna
Department of General Surgery, Regional Hospital in Sucha Beskidzka.
Pol Przegl Chir. 2011 Apr;83(4):227-30. doi: 10.2478/v10035-011-0035-3.
Pleomorphic adenoma (mixed tumor) is the most common type of salivary gland tumors, most often involving the parotid glands. The study presented a case of a giant pleomorphic adenoma of the submandibular gland in a 78-year old woman. Due to the initially slow and progressive growth (during a period of 25 years) without treatment, the tumor attained a size of 25×19×16 cm and a weight of 4 kg. The patient underwent surgery. The histopathological examination showed that the tumor was subject to malignant transformation: within the pleomorphic adenoma one observed mucoepidermoid carcinoma lesions of high-degree malignancy. In spite of the good postoperative esthetic and functional effect the patient was diagnosed with distant metastases to the lungs.
多形性腺瘤（混合瘤）是最常见的涎腺肿瘤类型，最常累及腮腺。该研究报告了一例78岁女性下颌下腺巨大多形性腺瘤的病例。由于最初未经治疗，肿瘤生长缓慢且呈进行性（长达25年），肿瘤大小达到25×19×16厘米，重量为4千克。患者接受了手术。组织病理学检查显示肿瘤已发生恶变：在多形性腺瘤内观察到高度恶性的黏液表皮样癌病变。尽管术后美观和功能效果良好，但患者仍被诊断为发生了肺远处转移。
