Kishimoto Nozomu, Okumi Masayoshi, Miyagawa Yasushi, Yoshioka Iwao, Sawada Kenzirou, Kimura Tadashi, Nonomura Norio
The Department of Urology, Osaka University Graduate School of Medicine.
Hinyokika Kiyo. 2011 Nov;57(11):657-60.
A 20-year-old woman referred to our hospital for further examination of primary amenorrhea with high levels of testosterone (998 ng/ml). Inspite of having normal female external genitalia, she had 5 cm deep blind-ending vagina, absence of uterus and ovaries with the karyotype of 46,XY. Abdominal magnetic resonance imaging localized bilateral intra abdominal structures, which indicated bilateral testes. Thus, she was diagnosed with androgen insensitivity syndrome(AIS) based on both clinical and karyotypic evidence. She underwent laparoscopic bilateral gonadalectomy through a single incision at the navel and histological examination showed intratubular germ cell neoplasia (ITGCN). Her postoperative course was uneventful with less pain and a small surgical wound was only at the navel. Laparoendoscopic single site surgery (LESS) can be considered a surgical procedure for gonadalectomy in AIS patients.
一名20岁女性因原发性闭经且睾酮水平高(998 ng/ml)转诊至我院进一步检查。尽管其女性外生殖器正常,但阴道盲端深5厘米,子宫和卵巢缺如,核型为46,XY。腹部磁共振成像定位了双侧腹内结构,提示双侧睾丸。因此,根据临床和核型证据,她被诊断为雄激素不敏感综合征(AIS)。她通过脐部单切口接受了腹腔镜双侧性腺切除术,组织学检查显示管内生殖细胞瘤(ITGCN)。她术后恢复顺利,疼痛较轻,仅脐部有一个小手术切口。单孔腹腔镜手术(LESS)可被视为AIS患者性腺切除术的一种手术方式。