使用单链构象多态性分析和直接测序法鉴定IX因子点突变 - Suppr

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超能文献

Identification of a factor IX point mutation using SSCP analysis and direct sequencing.

作者信息

Demers D B, Odelberg S J, Fisher L M

机构信息

Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298.

出版信息

Nucleic Acids Res. 1990 Sep 25;18(18):5575. doi: 10.1093/nar/18.18.5575.

DOI:10.1093/nar/18.18.5575

PMID:2216751

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC332266/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7b/332266/73f7f266e96b/nar00202-0225-a.jpg

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Nucleotide sequence of the gene for human factor IX (antihemophilic factor B).人凝血因子IX（抗血友病因子B）基因的核苷酸序列。

Biochemistry. 1985 Jul 2;24(14):3736-50. doi: 10.1021/bi00335a049.

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction.利用聚合酶链反应快速灵敏地检测点突变和DNA多态性。

Genomics. 1989 Nov;5(4):874-9. doi: 10.1016/0888-7543(89)90129-8.

Blood clotting factor IX BM Nagoya. Substitution of arginine 180 by tryptophan and its activation by alpha-chymotrypsin and rat mast cell chymase.凝血因子IX名古屋型。精氨酸180被色氨酸取代及其被α-糜蛋白酶和大鼠肥大细胞糜酶激活。

J Biol Chem. 1989 Dec 15;264(35):21257-65.

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Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.使用热稳定DNA聚合酶进行引物引导的DNA酶促扩增。

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