Akhmedov V A, P'iannikov V V, Keruchenko A L
Eksp Klin Gastroenterol. 2011(6):22-5.
The aim of the study was to compare the features of immune response in patients with alcoholic liver disease and non-alcoholic steatohepatitis.
There was investigated immune status of 46 patients with alcoholic liver disease and 34 patients with non-alcoholic steatohepatitis.
It was found the resemblance of the immune regulation of pathogenesis in both diseases. It was also established that in the history of alcoholic liver disease necrosis starts earlier because of loosing immune regulation of programmed cell death. This leads to forming liver cirrhosis in younger age.
本研究的目的是比较酒精性肝病和非酒精性脂肪性肝炎患者的免疫反应特征。
对46例酒精性肝病患者和34例非酒精性脂肪性肝炎患者的免疫状态进行了研究。
发现两种疾病发病机制的免疫调节存在相似之处。还确定在酒精性肝病的病程中,由于程序性细胞死亡的免疫调节丧失,坏死开始得更早。这导致在更年轻的年龄形成肝硬化。