Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
Clin Oral Implants Res. 2013 Apr;24(4):461-7. doi: 10.1111/j.1600-0501.2011.02352.x. Epub 2011 Dec 15.
A novel technique based on plasma immersion ion implantation (PIII) is presented to modify titanium implant surfaces.
Initially, the implants are cleaned with argon to remove contaminants and the nanostructures are created by the bombardment of the surface with a mix of noble gases. Desired crystal structure of the titanium is obtained by the implantation of oxygen on the contaminant-free surface with particular nanostructures.
In this study, turned implants modified by PIII revealed a high density of rutile-TiO2 nanostructures. Turned implants used as control revealed mainly microstructures and amorphous crystal structure. Surface roughness values were similar at the microscale for both turned and turned + PIII implants. Bone response was evaluated by removal torque tests of implants placed in the rabbit tibia and femur. After 4 weeks of healing, turned + PIII demonstrated higher removal torque values (P = 0.001) compared to turned implants.
The presence of rutile-TiO2 nanostructures may explain the improved bone formation to turned + PIII implants.
提出了一种基于等离子体浸没离子注入(PIII)的新技术来修饰钛植入物表面。
最初,使用氩气清洁植入物以去除污染物,并通过用混合的稀有气体轰击表面来创建纳米结构。通过在无污染物的表面上注入氧气并形成特定的纳米结构,可以获得所需的钛晶体结构。
在这项研究中,经过 PIII 修饰的车削植入物显示出高浓度的锐钛矿-TiO2 纳米结构。作为对照的车削植入物主要显示出微观结构和非晶态晶体结构。对于车削和车削+PIII 植入物,在微观尺度上,表面粗糙度值相似。通过将植入物放置在兔子的胫骨和股骨中进行移除扭矩测试来评估骨反应。在 4 周的愈合后,与车削植入物相比,车削+PIII 表现出更高的移除扭矩值(P=0.001)。
锐钛矿-TiO2 纳米结构的存在可能解释了车削+PIII 植入物中改善的骨形成。