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[感染肠道贾第虫的儿童小肠免疫分泌系统的体液反应]

[Humoral response of the immunologic secretory system of the small intestine in children infected with Giardia intestinalis].

作者信息

Swiatkowska E, Socha J, Siński E, Kluge P, Oralewska B, Kozłowski K

机构信息

Oddziału Gastroenterologii, UW w Warszawie.

出版信息

Pol Tyg Lek. 1990;45(8-9):167-9.

PMID:2216959
Abstract

Local humoral response of the intestinal mucosa was determined with secretory IgA levels and secretory component activity in enterocytes and duodenal content of 15 children infected with G. intestinalis. The obtained results were compared to those in 5 children with coeliac disease and 12 children with diarrhoea without lambliasis. Secretory IgA was increased in about 50% of children with lambliasis (in the remaining groups in 25% of children) to the values higher than that in the comparative groups. Secretory component activity was relatively high in the intestinal epithelium. Secretory component activity in the duodenal content was high in about 40% of children independently of the examined group. No correlation between the said variables was noted except positive correlation of secretory IgA levels and secretory component activity in the bile.

摘要

通过检测15例感染肠贾第虫的儿童肠黏膜的分泌型IgA水平、肠上皮细胞及十二指肠内容物中的分泌成分活性,来确定肠道黏膜的局部体液反应。将所得结果与5例乳糜泻患儿及12例无蓝氏贾第鞭毛虫感染腹泻患儿的结果进行比较。约50%的贾第虫感染患儿(其余组为25%的患儿)的分泌型IgA升高,其值高于比较组。肠道上皮中的分泌成分活性相对较高。无论受检组如何,约40%儿童十二指肠内容物中的分泌成分活性较高。除胆汁中分泌型IgA水平与分泌成分活性呈正相关外,未发现上述变量之间存在相关性。

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