Reback Cathy J, Shoptaw Steven
Friends Research Institute, Inc., Los Angeles, CA 90028, United States; UCLA Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA 90025, United States.
UCLA Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA 90025, United States; Department of Family Medicine, University of California at Los Angeles, Los Angeles, CA 90025, United States.
Addict Behav. 2014 Aug;39(8):1286-91. doi: 10.1016/j.addbeh.2011.11.029. Epub 2011 Nov 26.
This study compared outcomes in methamphetamine use and sexual risk behaviors from a modified gay-specific, cognitive behavioral therapy (GCBT) combined with a low-cost contingency management (CM; [GCBT+CM]) intervention to prior findings from clinical trials of the original GCBT. Effect sizes for primary outcomes were compared using meta analysis. Comparisons of effect sizes at end of treatment showed the modified GCBT+CM produced significantly fewer consecutive weeks of methamphetamine abstinence (-0.44, CI: -0.79, -0.09) and fewer male sexual partners (-0.36, CI: -0.71, -0.02) than the first trial of GCBT, and more days of methamphetamine use (0.35, CI: 0.02, 0.68) than the second trial of GCBT. At 26-week follow-up, the modified GCBT+CM produced greater effects in reducing the number of male sexual partners (-0.54, CI: -0.89, -0.19; -0.51, CI: -0.84, -0.18). The original GCBT produced more and mostly short-term beneficial drug use outcomes, though sexual behavior changes consistently favored the modified GCBT+CM. On balance, most benefits are retained with the modified GCBT+CM intervention.
本研究比较了一种改良的针对男同性恋者的认知行为疗法(GCBT)与低成本应急管理(CM;[GCBT+CM])相结合的干预措施在甲基苯丙胺使用和性风险行为方面的结果与原始GCBT临床试验的先前结果。使用荟萃分析比较了主要结局的效应大小。治疗结束时效应大小的比较表明,改良后的GCBT+CM与首次GCBT试验相比,甲基苯丙胺戒断的连续周数显著减少(-0.44,CI:-0.79,-0.09),男性性伴侣数量减少(-0.36,CI:-0.71,-0.02),且与第二次GCBT试验相比,甲基苯丙胺使用天数增加(0.35,CI:0.02,0.68)。在26周的随访中,改良后的GCBT+CM在减少男性性伴侣数量方面产生了更大的效果(-0.54,CI:-0.89,-0.19;-0.51,CI:-0.84,-0.18)。原始的GCBT产生了更多且大多是短期有益的药物使用结果,尽管性行为改变一直有利于改良后的GCBT+CM。总体而言,改良后的GCBT+CM干预措施保留了大部分益处。