Sindelar Jody, Elbel Brian, Petry Nancy M
Yale School of Public Health and Yale Medical School, CT 06520, USA.
Addiction. 2007 Feb;102(2):309-16. doi: 10.1111/j.1360-0443.2006.01689.x.
To assess the relative cost-effectiveness of lower versus higher cost prize-based contingency management (CM) treatments for cocaine abuse.
Cost-effectiveness analyses based on resource utilization, unit costs and outcomes from a previous CM efficacy trial.
Two community-based treatment centers.
Patients (n = 120) enrolled in out-patient treatment for cocaine abuse.
Random assignment to one of three 12-week treatment conditions: standard treatment (STD) alone or two variants of STD combined with prize based CM. In CM, drawing for prizes was available to those submitting drug-free urine samples and completing goal-related activities. There were two levels of pay-out (referred to as $80 versus $240) based on the potential value of prizes won.
Costs per participant associated with counseling utilization, urine and breathalyzer testing, and operation of the prize-drawing procedure were derived from a survey conducted at 16 clinics that had participated in CM studies. The three measures of effectiveness were: (1) longest duration of consecutive abstinence; (2) percentage completing treatment; and (3) percentage of samples drug-free.
The higher magnitude CM produced outcomes at a lower per unit cost than did the lower magnitude prize CM treatment. This was the case for all three outcome measures examined and held across various assumptions in the sensitivity analysis.
Cost-effectiveness analyses can inform policy decisions regarding selection of one treatment model over another. Decisions on adoption of new evidence-based treatments would be aided by more information on society's willingness to pay for incremental gains in effectiveness.
评估低成本与高成本的基于奖励的应急管理(CM)疗法治疗可卡因滥用的相对成本效益。
基于资源利用、单位成本和先前CM疗效试验结果进行成本效益分析。
两个社区治疗中心。
120名因可卡因滥用而参加门诊治疗的患者。
随机分配到三种为期12周的治疗方案之一:单独的标准治疗(STD)或两种STD变体与基于奖励的CM相结合。在CM中,提交无毒品尿液样本并完成与目标相关活动的人可以参与抽奖。根据赢得奖品的潜在价值,有两个奖励水平(称为80美元与240美元)。
每位参与者与咨询利用、尿液和呼气酒精含量测试以及抽奖程序操作相关的成本来自对16个参与CM研究的诊所进行的一项调查。三种有效性指标分别为:(1)连续禁欲的最长持续时间;(2)完成治疗的百分比;(3)无毒品样本的百分比。
高剂量CM治疗的单位成本低于低剂量奖励CM治疗,三种检测的结果指标均如此,且在敏感性分析的各种假设下均成立。
成本效益分析可为选择一种治疗模式而非另一种治疗模式的政策决策提供参考。关于采用新的循证治疗方法的决策,若能获得更多关于社会为有效性的增量收益支付意愿的信息将有所帮助。