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硫喷妥钠与依托咪酯联合用于麻醉诱导的评估。

An evaluation of combining thiopentone and etomidate for the induction of anaesthesia.

作者信息

Slater R M, Pollard B J, Young T M, Hunt L P

机构信息

Department of Anaesthesia, University of Manchester, UK.

出版信息

Postgrad Med J. 1990 Jul;66(777):539-42. doi: 10.1136/pgmj.66.777.539.

Abstract

The characteristics of three combinations of thiopentone and etomidate [in the ratios of thiopentone (mg):etomidate (mg) of 5:1, 13:1 and 25:1] have been compared with the individual agents alone for the induction of anaesthesia. The incidence of pain on injection and abnormal movements was less with the combination containing the highest ratio of thiopentone to etomidate, when compared to etomidate alone. The mixtures did not otherwise confer any advantages over the individual agents.

摘要

已将硫喷妥钠和依托咪酯三种组合[硫喷妥钠(毫克):依托咪酯(毫克)比例为5:1、13:1和25:1]的特性与单独使用这两种药物诱导麻醉的情况进行了比较。与单独使用依托咪酯相比,硫喷妥钠与依托咪酯比例最高的组合注射时疼痛和异常运动的发生率更低。除此之外,这些混合物与单独使用药物相比没有任何优势。

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本文引用的文献

1
Etomidate: a foreshortened clinical trial.依托咪酯:一项缩短的临床试验。
Anaesth Intensive Care. 1980 Nov;8(4):479-83. doi: 10.1177/0310057X8000800417.
2
Etomidate: an 'immunologically safe' anaesthetic agent.依托咪酯:一种“免疫安全”的麻醉剂。
Anaesthesia. 1983 Jul;38 Suppl:34-8. doi: 10.1111/j.1365-2044.1983.tb15174.x.
4
The prevention of etomidate-induced myoclonus.依托咪酯诱发肌阵挛的预防
Anaesthesia. 1984 Jan;39(1):70-1. doi: 10.1111/j.1365-2044.1984.tb09471.x.
5
Etomidate, a new water-soluble non-barbiturate intravenous induction agent.
Lancet. 1975 Apr 26;1(7913):955-6. doi: 10.1016/s0140-6736(75)92011-5.

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