Slater R M, Pollard B J, Young T M, Hunt L P
Department of Anaesthesia, University of Manchester, UK.
Postgrad Med J. 1990 Jul;66(777):539-42. doi: 10.1136/pgmj.66.777.539.
The characteristics of three combinations of thiopentone and etomidate [in the ratios of thiopentone (mg):etomidate (mg) of 5:1, 13:1 and 25:1] have been compared with the individual agents alone for the induction of anaesthesia. The incidence of pain on injection and abnormal movements was less with the combination containing the highest ratio of thiopentone to etomidate, when compared to etomidate alone. The mixtures did not otherwise confer any advantages over the individual agents.
已将硫喷妥钠和依托咪酯三种组合[硫喷妥钠(毫克):依托咪酯(毫克)比例为5:1、13:1和25:1]的特性与单独使用这两种药物诱导麻醉的情况进行了比较。与单独使用依托咪酯相比,硫喷妥钠与依托咪酯比例最高的组合注射时疼痛和异常运动的发生率更低。除此之外,这些混合物与单独使用药物相比没有任何优势。