• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下丘脑-垂体-性腺轴中基因表达的社会调节。

Social regulation of gene expression in the hypothalamic-pituitary-gonadal axis.

机构信息

Department of Biology, Stanford University, Stanford, California, USA.

出版信息

Physiology (Bethesda). 2011 Dec;26(6):412-23. doi: 10.1152/physiol.00032.2011.

DOI:10.1152/physiol.00032.2011
PMID:22170959
Abstract

Reproduction is a critically important event in every animals' life and in all vertebrates is controlled by the brain via the hypothalamic-pituitary-gonadal (HPG) axis. In many species, this axis, and hence reproductive fitness, can be profoundly influenced by the social environment. Here, we review how the reception of information in a social context causes genomic changes at each level of the HPG axis.

摘要

繁殖是每个动物生命中至关重要的事件,在所有脊椎动物中,它都受到大脑通过下丘脑-垂体-性腺(HPG)轴的控制。在许多物种中,这个轴,以及生殖适应性,都可以被社会环境深刻地影响。在这里,我们回顾了在社会环境中信息的接收如何导致 HPG 轴各个水平的基因组变化。

相似文献

1
Social regulation of gene expression in the hypothalamic-pituitary-gonadal axis.下丘脑-垂体-性腺轴中基因表达的社会调节。
Physiology (Bethesda). 2011 Dec;26(6):412-23. doi: 10.1152/physiol.00032.2011.
2
Modulation of the hypothalamic-pituitary-gonadal axis by selective ligands of the KISS1R.KISS1R选择性配体对下丘脑-垂体-性腺轴的调节
Curr Opin Investig Drugs. 2010 Apr;11(4):432-9.
3
The origins of the vertebrate hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-thyroid (HPT) endocrine systems: new insights from lampreys.脊椎动物下丘脑-垂体-性腺(HPG)和下丘脑-垂体-甲状腺(HPT)内分泌系统的起源:七鳃鳗带来的新见解。
Gen Comp Endocrinol. 2009 Mar;161(1):20-9. doi: 10.1016/j.ygcen.2008.11.023. Epub 2008 Dec 3.
4
Orexin receptor expression in the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes of free-living European beavers (Castor fiber L.) in different periods of the reproductive cycle.自由生活的欧洲河狸(Castor fiber L.)在生殖周期不同阶段下丘脑-垂体-肾上腺轴和下丘脑-垂体-性腺轴中食欲素受体的表达
Gen Comp Endocrinol. 2017 Jan 1;240:103-113. doi: 10.1016/j.ygcen.2016.09.013. Epub 2016 Sep 21.
5
Widespread alterations to hypothalamic-pituitary-gonadal (HPG) axis signaling underlie high temperature reproductive inhibition in the eurythermal sheepshead minnow (Cyprinodon variegatus).广温性的海湾鲱鱼(Cyprinodon variegatus)高温下繁殖受抑制的根本原因是下丘脑-垂体-性腺(HPG)轴信号传导的广泛改变。
Mol Cell Endocrinol. 2021 Nov 1;537:111447. doi: 10.1016/j.mce.2021.111447. Epub 2021 Aug 29.
6
Molecular regulation of hypothalamus-pituitary-gonads axis in males.男性下丘脑-垂体-性腺轴的分子调控
Gene. 2014 Nov 1;551(1):15-25. doi: 10.1016/j.gene.2014.08.048. Epub 2014 Aug 26.
7
Kisspeptin2 stimulates the HPG axis in immature Nile tilapia (Oreochromis niloticus).亲吻素2刺激未成熟尼罗罗非鱼(尼罗口孵非鲫)的下丘脑-垂体-性腺轴。
Comp Biochem Physiol B Biochem Mol Biol. 2016 Dec;202:31-38. doi: 10.1016/j.cbpb.2016.07.009. Epub 2016 Aug 3.
8
60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-pituitary-gonadal axis.神经内分泌学60年:下丘脑 - 垂体 - 性腺轴
J Endocrinol. 2015 Aug;226(2):T41-54. doi: 10.1530/JOE-15-0113. Epub 2015 Apr 21.
9
Physiological consequences of social descent: studies in Astatotilapia burtoni.社会地位下降的生理后果:对布氏非鲫的研究
J Endocrinol. 2006 Jul;190(1):183-90. doi: 10.1677/joe.1.06755.
10
Tonic activation of brain GnRH immunoreactivity despite reduction of peripheral reproductive parameters in opportunistically breeding zebra finches.尽管机会性繁殖的斑胸草雀外周生殖参数降低,但大脑促性腺激素释放激素免疫反应性呈紧张性激活。
Brain Behav Evol. 2006;67(3):123-34. doi: 10.1159/000090977. Epub 2006 Jan 13.

引用本文的文献

1
Brain-associated alterations of Hippo pathway transcription in early maturing Atlantic salmon.早熟大西洋鲑鱼中与大脑相关的Hippo信号通路转录变化
BMC Ecol Evol. 2025 May 26;25(1):53. doi: 10.1186/s12862-025-02398-4.
2
Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP).基于转录组学分析暴露于磷酸三(2-氯乙基)酯(TCEP)后大菱鲆(Scophthalmus maximus)的神经毒性和生殖效应。
BMC Genomics. 2025 Jan 15;26(1):38. doi: 10.1186/s12864-024-11061-z.
3
Microplastics bioaccumulation in fish: Its potential toxic effects on hematology, immune response, neurotoxicity, oxidative stress, growth, and reproductive dysfunction.
微塑料在鱼类中的生物累积:其对血液学、免疫反应、神经毒性、氧化应激、生长及生殖功能障碍的潜在毒性作用。
Toxicol Rep. 2024 Dec 9;14:101854. doi: 10.1016/j.toxrep.2024.101854. eCollection 2025 Jun.
4
Exposure to novel females increases fecundity in adult male prairie voles.接触新的雌性会提高成年雄性草原田鼠的繁殖力。
bioRxiv. 2024 Dec 20:2024.12.18.627569. doi: 10.1101/2024.12.18.627569.
5
Oxidative stress in the brain is regulated by social status in a highly social cichlid fish.在一种高度群居的丽鱼科鱼类中,大脑中的氧化应激受社会地位调控。
Front Behav Neurosci. 2024 Nov 26;18:1477984. doi: 10.3389/fnbeh.2024.1477984. eCollection 2024.
6
Regulatory Involvement of Kisspeptin in Energy Balance and Reproduction.kisspeptin在能量平衡和生殖中的调节作用
Cell Biochem Biophys. 2025 Mar;83(1):247-261. doi: 10.1007/s12013-024-01537-w. Epub 2024 Sep 26.
7
Reconsidering reproductive patterns in a model dissociated species, the red-sided garter snake: Sex-specific and seasonal changes in gonadal steroidogenic gene expression.重新考虑分离物种红边束带蛇的生殖模式:性腺类固醇生成基因表达的性别特异性和季节性变化。
Front Endocrinol (Lausanne). 2023 Mar 13;14:1135535. doi: 10.3389/fendo.2023.1135535. eCollection 2023.
8
Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish.唑菌酯影响斑马鱼社会行为和繁殖的分子机制。
Int J Environ Res Public Health. 2023 Feb 22;20(5):3928. doi: 10.3390/ijerph20053928.
9
Presence, Tissue Localization, and Gene Expression of the Adiponectin Receptor 1 in Testis and Accessory Glands of Male Rams during the Non-Breeding Season.非繁殖季节雄性绵羊睾丸和附属腺体中脂联素受体1的存在、组织定位及基因表达
Animals (Basel). 2023 Feb 9;13(4):601. doi: 10.3390/ani13040601.
10
Transcriptomes of testis and pituitary from male Nile tilapia (O. niloticus L.) in the context of social status.社会地位背景下雄性尼罗罗非鱼(Oreochromis niloticus L.)睾丸和脑垂体转录组
PLoS One. 2022 May 11;17(5):e0268140. doi: 10.1371/journal.pone.0268140. eCollection 2022.