van Oosten Erik M, Furqan Muhammed Ali, Redfearn Damian P, Simpson Christopher S, Fitzpatrick Michael, Michael Kevin A, Hopman Wilma M, Baranchuk Adrian
Cardiology Division, Kingston General Hospital, Queen's University, 76 Stuart St., Kingston, Ontario, Canada, K7L 2V7.
J Interv Card Electrophysiol. 2012 Jun;34(1):73-8. doi: 10.1007/s10840-011-9644-3. Epub 2011 Dec 17.
Sleep apnea (SA) has been associated with atrial fibrillation (AF) and has been found to be a predictor of AF recurrence after successful pulmonary vein isolation. No investigations have been carried out to determine the prevalence of SA in patients with typical atrial flutter (AFL) and the impact of SA on AFL recurrence after AFL ablation. Our aim is to determine if SA is a predictor of recurrence of AFL and/or atrial arrhythmias in patients who have undergone AFL ablation.
This study used a retrospective electronic chart review analysis of consecutive right-sided isthmus-dependent AFL referred for ablation over a 2-year period. Recurrent atrial arrhythmias were classified as AFL, AF, or other arrhythmias. SA prevalence was determined.
We included 122 consecutive patients undergoing AFL ablation between January 2008 and December 2009. Mean follow-up was 28.3 ± 6.4 months. Males were 75.4%, had a mean age of 68.3 ± 10.4 years, hypertension 65%, and structural heart disease 42%. Prevalence of SA was 27%. Recurrence of AFL was observed in 9.8%, recurrence of AF was observed in 22.1%, and other arrhythmias 4.9%. SA was not a predictor of AFL recurrence (6.1% vs. 11.2%; p = 0.39). SA was neither a predictor of AF nor of other arrhythmia recurrences. Variables associated with AFL recurrence were: no history of preablation antiarrhythmic drugs (18.8% vs. 6.7%; p = 0.04) and lower BMI (27.07 kg/m(2) vs. 30.87 kg/m(2); p = 0.04).
Prevalence of SA in patients with AFL was 27%. SA was not found to be a predictor of AFL recurrence after successful AFL ablation.
睡眠呼吸暂停（SA）与心房颤动（AF）相关，并且已被发现是肺静脉隔离成功后房颤复发的一个预测因素。尚未开展研究来确定典型心房扑动（AFL）患者中SA的患病率以及SA对AFL消融术后AFL复发的影响。我们的目的是确定SA是否为接受AFL消融的患者中AFL和/或房性心律失常复发的预测因素。
本研究采用回顾性电子病历审查分析，对连续2年转诊接受消融的右侧峡部依赖性AFL患者进行分析。复发性房性心律失常分为AFL、AF或其他心律失常。确定SA患病率。
我们纳入了2008年1月至2009年12月期间连续接受AFL消融的122例患者。平均随访时间为28.3±6.4个月。男性占75.4%，平均年龄为68.3±10.4岁，高血压患者占65%，有结构性心脏病的患者占42%。SA患病率为27%。观察到AFL复发率为9.8%，AF复发率为22.1%，其他心律失常复发率为4.9%。SA不是AFL复发的预测因素（6.1%对vs.11.2%；p = 0.39）。SA既不是AF复发的预测因素，也不是其他心律失常复发的预测因素。与AFL复发相关的变量为：消融前无抗心律失常药物治疗史（18.8%对vs.6.7%；p = 0.04）和较低的体重指数（27.07kg/m²对vs.30.87kg/m²；p = 0.04）。
AFL患者中SA的患病率为27%。成功进行AFL消融后，未发现SA是AFL复发的预测因素。
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