School of Medicine, université de La-Méditerrané, hôpital Nord, Division of Cardiology, Marseille, France.
Arch Cardiovasc Dis. 2011 Oct;104(10):530-5. doi: 10.1016/j.acvd.2011.07.003. Epub 2011 Oct 14.
Atrial flutter (AFL) and atrial fibrillation (AF) are "fellow-travellers". AF may be a stable, "isolated" rhythm, a bridge between sinus rhythm and AF, or both arrhythmias can coexist. Whether the characteristics of isolated AFL are different from those of patients with AFL combined with AF is still unclear.
To compare the clinical characteristics of patients with isolated AFL to those of patients with AFL combined with AF, in a series of patients referred for AFL ablation.
Seventy-six consecutive patients (mean age 66.9±12.2 years; 53 men) with a history of electrocardiogram-documented paroxysmal or persistent AFL, referred for catheter ablation, underwent clinical work-up including bidimensional echocardiogram. Patients were subdivided into group I (44 with isolated AFL) and group II (32 with AFL and a history of AF).
Underlying heart disease was present in 62 patients (81.6%). Hypertension was the most common cardiac disorder (n=44, 57.9%) and was more prevalent in group II than in group I (75.0% vs 45.5%; P=0.01). Prevalence of prior cardiac surgery was higher in group I (22.7% vs 6.3%; P=0.04). AFL was persistent in 35 group I patients and 17 group II patients (79.5% vs 53.1%; P=0.01). Class I or III antiarrhythmic drug use was more frequent in group II (84.4% vs 45.5%; P=0.001).
This study showed significant differences between patients with isolated AFL and those with AFL combined with AF, in the prevalence of underlying heart disease and the use of antiarrhythmic medication, which were higher when both atrial arrhythmias were combined. In turn, the history of cardiac surgery (including atriotomy), was more common in patients with isolated AFL than in those with AFL combined with AF.
心房扑动(AFL)和心房颤动(AF)是“结伴旅行者”。AF 可能是一种稳定的、“孤立的”节律,是窦性节律和 AF 之间的桥梁,或者两种心律失常可以共存。孤立性 AFL 的特征是否与 AFL 合并 AF 的患者不同仍不清楚。
比较孤立性 AFL 患者与 AFL 合并 AF 患者的临床特征,这些患者均因 AFL 消融而接受治疗。
76 例连续患者(平均年龄 66.9±12.2 岁;53 名男性)均有心电图记录的阵发性或持续性 AFL 病史,接受导管消融治疗,进行临床评估,包括二维超声心动图。患者分为 I 组(44 例孤立性 AFL)和 II 组(32 例 AFL 合并 AF 病史)。
62 例(81.6%)存在基础心脏病。高血压是最常见的心脏疾病(n=44,57.9%),在 II 组比 I 组更常见(75.0%比 45.5%;P=0.01)。I 组有更多的既往心脏手术史(22.7%比 6.3%;P=0.04)。35 例 I 组患者和 17 例 II 组患者 AFL 持续存在(79.5%比 53.1%;P=0.01)。II 组患者更常使用 I 类或 III 类抗心律失常药物(84.4%比 45.5%;P=0.001)。
本研究表明,孤立性 AFL 患者与 AFL 合并 AF 患者之间存在显著差异,在基础心脏病的患病率和抗心律失常药物的使用方面存在差异,当两种房性心律失常同时存在时,这些差异更为明显。相反,在孤立性 AFL 患者中,心脏手术(包括心房切开术)的病史比 AFL 合并 AF 患者更常见。