Stanford University; the University of Texas M.D. Anderson Cancer Center.
Blood. 2011 Dec 15;118(25):6482-4. doi: 10.1182/blood-2011-10-382630.
In this issue of Blood, Cutler and colleagues present evidence that donor-specific anti-HLA antibodies are associated with graft failure in double umbilical cord blood transplantation (CBT).1 Engraftment of donor cells is the first important step in successful transplantation and, until recently, the causes of engraftment failure remained elusive.
在本期《Blood》中,Cutler 及其同事提出了证据表明,供体特异性抗 HLA 抗体与双脐血干细胞移植(CBT)中的移植物失败有关。1 供体细胞的植入是成功移植的第一步,直到最近,植入失败的原因仍难以捉摸。