Carrion Juliana Zimmermann, Fortes Filho João Borges, Tartarella Marcia Beatriz, Zin Andrea, Jornada Ignozy Dorneles
Program for the Prevention of Blindness due to Retinopathy of Prematurity, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Clin Ophthalmol. 2011;5:1687-95. doi: 10.2147/OPTH.S25166. Epub 2011 Dec 1.
The purpose of this work was to review the studies published over the last 10 years concerning the prevalence of retinopathy of prematurity (ROP) in Latin American countries, to determine if there was an improvement in ROP prevalence rates in that period, and to identify the inclusion criteria for patients at risk of developing ROP in the screening programs. A total of 33 studies from ten countries published between 2000 and 2010 were reviewed. Prevalence of any ROP stage in the regions considered ranged from 6.6% to 82%; ROP severe enough to require treatment ranged from 1.2% to 23.8%. There was no routine screening for ROP, and there was a lack of services for treatment of the disease in many countries. Inclusion criteria for patients in the studies ranged between birth weight ≤ 1500 g and ≤ 2000 g and gestational age ≤ 32 and <37 weeks. Use of different inclusion criteria regarding birth weight and gestational age in several Latin American studies hindered comparative analysis of the published data. Highly restrictive selection criteria for ROP screening in relation to birth weight and gestational age should not be used throughout most Latin American countries because of their different social characteristics and variable neonatal care procedures. The studies included in this review failed to provide adequate information to determine if the prevalence of ROP has decreased in Latin America.
这项工作的目的是回顾过去10年发表的关于拉丁美洲国家早产儿视网膜病变(ROP)患病率的研究,确定该时期ROP患病率是否有所改善,并确定筛查项目中ROP高危患者的纳入标准。对2000年至2010年间发表的来自10个国家的33项研究进行了回顾。在所考虑的地区,任何ROP阶段的患病率在6.6%至82%之间;严重到需要治疗的ROP患病率在1.2%至23.8%之间。许多国家没有对ROP进行常规筛查,且缺乏该疾病的治疗服务。研究中患者的纳入标准在出生体重≤1500g至≤2000g以及胎龄≤32周和<37周之间。拉丁美洲的几项研究在出生体重和胎龄方面使用了不同的纳入标准,这阻碍了对已发表数据的比较分析。由于大多数拉丁美洲国家具有不同的社会特征和多样的新生儿护理程序,因此不应在这些国家普遍使用与出生体重和胎龄相关的高度严格RO的P筛查选择标准。本综述纳入的研究未能提供足够信息来确定拉丁美洲ROP患病率是否有所下降。