Berisa F, Beaman M, Adu D, McGonigle R J, Michael J, Downing R, Fielding J W, Dunn J
Department of Nephrology, Queen Elizabeth Hospital, Edgbaston, Birmingham.
Q J Med. 1990 Jul;76(279):689-98.
This study analyses the prognostic factors associated with survival in 70 patients who developed acute renal failure following surgery for an aortic aneurysm. Forty-nine patients (70 per cent) had surgery for a ruptured aortic aneurysm and 21 patients (30 per cent) had an elective procedure. Fifty-nine patients received haemodialysis. Thirty-three patients (47 per cent) survived the episode of acute renal failure. Six of these thirty-three patients died within three months of recovering from acute renal failure, giving an overall survival of 27/70 (39 per cent). A stepwise logistic regression analysis showed that the following factors significantly adversely affected survival: a need for inotropic support, ventilation for more than three days and age over 65 years. A model developed using these variables provided a basis for predicting outcome.
本研究分析了70例主动脉瘤手术后发生急性肾衰竭患者的生存相关预后因素。49例(70%)患者因主动脉瘤破裂接受手术,21例(30%)患者接受择期手术。59例患者接受了血液透析。33例(47%)患者在急性肾衰竭发作后存活。这33例患者中有6例在从急性肾衰竭恢复后的三个月内死亡,总体生存率为27/70(39%)。逐步逻辑回归分析表明,以下因素对生存有显著不利影响:需要使用血管活性药物支持、通气超过三天以及年龄超过65岁。使用这些变量建立的模型为预测结果提供了依据。