Del Giudice Pascal, Tattevin Pierre, Etienne Jérôme
Hôpital Bonnet, Infectious Diseases and Dermatology Unit, Fréjus, France.
Presse Med. 2012 Jul;41(7-8):713-20. doi: 10.1016/j.lpm.2011.10.022. Epub 2011 Dec 16.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged worldwide. These CA-MRSA are different from classical hospital-acquired MRSA. They share common characteristics: they affect mainly young subjects, without past medical history. The majority of strains produce the Panton-Valentine leukocidin. They are mainly responsible for suppurative skin infections and rarely for invasive infections such as necrotizing pneumonia. The situation in the US is alarming with a main circulating clone the USA300 clone, whereas in Europe, the diffusion of CA-MRSA strains remains limited. It is important to take advantage of the experience acquired from the US to limit the potential spread of such CA-MRSA strains.
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）已在全球出现。这些CA-MRSA与经典的医院获得性MRSA不同。它们具有共同特征：主要影响无既往病史的年轻人群。大多数菌株产生杀白细胞素。它们主要导致化脓性皮肤感染，很少引起侵袭性感染，如坏死性肺炎。美国的情况令人担忧，主要流行克隆为USA300克隆，而在欧洲，CA-MRSA菌株的传播仍然有限。利用从美国获得的经验来限制此类CA-MRSA菌株的潜在传播很重要。
