Wouters E F, Mostert R, Polko A H, Visser B F
Department of Pulmonary Diseases, University Limburg, Maastricht, The Netherlands.
Respir Med. 1990 May;84(3):205-9. doi: 10.1016/s0954-6111(08)80036-4.
The application of forced oscillations has been introduced as a noninvasive method to measure the impedance of the respiratory system. Impedance can be partitioned into a real part or resistance and an imaginary part or reactance. The reactance depends on the elastic and inertial properties of the respiratory system. In the present study, resistance and reactance obtained in a frequency spectrum between 4 and 52 Hz were compared with maximal forced expiratory spirometry in 100 out-patients, aged 18-70 years. Resonant frequency and frequency dependence of resistance correlated significantly with selected parameters of the forced expiratory flow volume curve: correlation coefficient values ranged from 0.492 between frequency dependence and FVC and 0.668 between resonant frequency and FEV1. No correlation between average resistance and spirometric parameters reached a statistically significant level. No marked difference was observed between spirometric parameters depending on the early or effort-dependent portion and those parameters depending on the late or effort independent portion of the maximum forced expiration. It can be concluded that each measurement procedure reveals different but characteristic information about the mechanical behaviour and properties of the respiratory system.
强迫振荡技术已被引入作为一种测量呼吸系统阻抗的非侵入性方法。阻抗可分为实部即阻力和虚部即电抗。电抗取决于呼吸系统的弹性和惯性特性。在本研究中，对100名年龄在18至70岁的门诊患者在4至52赫兹频谱范围内获得的阻力和电抗与最大用力呼气肺活量测定法进行了比较。共振频率和阻力的频率依赖性与用力呼气流量容积曲线的选定参数显著相关：相关系数值在频率依赖性与用力肺活量之间为0.492，在共振频率与第1秒用力呼气量之间为0.668。平均阻力与肺量计参数之间的相关性未达到统计学显著水平。根据最大用力呼气的早期或用力依赖部分的肺量计参数与根据晚期或用力独立部分的参数之间未观察到明显差异。可以得出结论，每种测量方法都揭示了关于呼吸系统力学行为和特性的不同但具有特征性的信息。
