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人类弓蛔虫病中的肝脓肿

Liver abscess in human toxocariasis.

作者信息

Treska V, Sutnar A, Mukensnabl P, Manakova T, Sedlacek D, Mirka H, Ferda J

机构信息

Department of Surgery, School of Medicine, University Hospital, Pilsen, Czech Republic.

出版信息

Bratisl Lek Listy. 2011;112(11):644-7.

PMID:22180993
Abstract

BACKGROUND

Toxocariasis is a parasitic infection caused by Toxocara canis or Toxocara cati. It is distributed worldwide. Liver is the main organ affected by Toxocara infection, typically with multiple eosinophilic infiltrates. Liver abscess formation is a very rare condition.

METHOD

The authors report on a case of Toxocariasis infection with abscess formation in the right liver lobe. The diagnosis was made upon patient's history, clinical examination, use of ultrasonography, computed tomography and especially upon positive serologic test and hypereosinophilia. After unsuccessful conservative treatment (Mebendazole, antibiotics and corticoids), right hepatectomy was performed.

RESULTS

The postoperative course was complicated by biliary fistula in the resection area. The complication was successfully managed by temporary stent implantation to the left hepatic duct. Six months after the operation, the patient is with no complications.

CONCLUSION

Liver abscess formation is a rare condition associated with Toxocara infection. It is still a matter of debate whether liver abscess results from severe parasitic infection or whether human toxocariasis is a predisposing cause of pyogenic liver abscess formation. Liver resection is the only treatment option when sepsis fails to respond to conservative treatment (Fig. 5, Ref. 22).

摘要

背景

弓蛔虫病是由犬弓蛔虫或猫弓蛔虫引起的寄生虫感染。该病在全球范围内均有分布。肝脏是受弓蛔虫感染影响的主要器官,通常会出现多处嗜酸性粒细胞浸润。肝脓肿形成是一种非常罕见的情况。

方法

作者报告了一例右肝叶出现脓肿形成的弓蛔虫病感染病例。根据患者病史、临床检查、超声检查、计算机断层扫描结果,特别是血清学检测呈阳性和嗜酸性粒细胞增多症做出诊断。在保守治疗(甲苯达唑、抗生素和皮质类固醇)失败后,进行了右肝切除术。

结果

术后病程因切除部位出现胆瘘而复杂化。通过向左肝管临时植入支架成功处理了该并发症。术后六个月,患者无并发症。

结论

肝脓肿形成是与弓蛔虫感染相关的罕见情况。肝脓肿是由严重寄生虫感染引起,还是人类弓蛔虫病是化脓性肝脓肿形成的易感因素,目前仍存在争议。当败血症对保守治疗无反应时,肝切除术是唯一的治疗选择(图5,参考文献22)。

相似文献

1
Liver abscess in human toxocariasis.人类弓蛔虫病中的肝脓肿
Bratisl Lek Listy. 2011;112(11):644-7.
2
[A case of hepatic abscess caused by toxocara].一例由弓首蛔虫引起的肝脓肿
Korean J Hepatol. 2007 Sep;13(3):409-13. doi: 10.3350/kjhep.2007.13.3.409.
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Atypical -Induced Hepatic Visceral Larva Migrans: Diagnostic Challenges and Literature Review.非典型性内脏幼虫移行症:诊断挑战与文献综述。
Korean J Gastroenterol. 2024 Jun 25;83(6):247-252. doi: 10.4166/kjg.2024.051.
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Human toxocariasis and pyogenic liver abscess: a possible association.人类弓蛔虫病与化脓性肝脓肿:一种可能的关联。
Am J Gastroenterol. 2001 Feb;96(2):563-6. doi: 10.1111/j.1572-0241.2001.03471.x.
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[Eosinophilic liver abscess caused by Toxocara canis].犬弓首蛔虫引起的嗜酸性粒细胞性肝脓肿
Korean J Gastroenterol. 2011 Oct 25;58(4):226-8. doi: 10.4166/kjg.2011.58.4.226.
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Hepatic toxocariasis: a rare cause of right upper abdominal pain in the emergency department.肝弓首蛔虫病:急诊科右上腹疼痛的罕见病因。
Turkiye Parazitol Derg. 2013;37(2):151-3. doi: 10.5152/tpd.2013.33.
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[Estimation of eosinophilia, immunoglobulin E and eosinophilic cationic protein concentration during the treatment of toxocariasis].[弓蛔虫病治疗期间嗜酸性粒细胞增多、免疫球蛋白E及嗜酸性粒细胞阳离子蛋白浓度的评估]
Wiad Parazytol. 2008;54(3):225-30.
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Enhanced resolution of eosinophilic liver abscess associated with toxocariasis by albendazole treatment.阿苯达唑治疗可提高与弓蛔虫病相关的嗜酸性粒细胞性肝脓肿的分辨率。
Korean J Gastroenterol. 2015 Apr;65(4):222-8. doi: 10.4166/kjg.2015.65.4.222.
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Fine needle aspiration diagnosis of necrotizing eosinophilic abscess clinically mimicking hepatic neoplasia: a case report.细针穿刺诊断临床疑似肝肿瘤的坏死性嗜酸性脓肿:一例报告
Acta Cytol. 2010 Jan-Feb;54(1):60-2. doi: 10.1159/000324968.
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[Uveitis caused by Toxocara canis].犬弓首蛔虫引起的葡萄膜炎
Acta Med Croatica. 2006;60(1):63-6.

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Space Occupying Lesion in the Liver Caused by Hepatic Visceral Larva Migrans: A Case Report.肝脏内脏幼虫移行症引起的肝占位性病变:一例报告。
Am J Trop Med Hyg. 2018 Dec;99(6):1602-1605. doi: 10.4269/ajtmh.18-0199.