Defence Research Laboratory, Defence R & D Organisation, Tezpur, Sonitpur, Assam, India.
Int J Dermatol. 2012 Jan;51(1):63-6. doi: 10.1111/j.1365-4632.2011.05035.x.
Simulium dermatitis is a common problem in humans and animals in areas where Simulium species occur. It is characterized by chronic eruptions of pruritic papules, vesicles, and erythematous wheals resulting from a hypersensitivity reaction to biting of simuliids or blackflies. It can result in severe skin complications where the man-biting species of Simulium are available.
We report two clinical cases of Simulium dermatitis from the North-Eastern region of India. Histopathological study was carried out in one of the cases and the other one was successfully treated with medication.
Clinical features like intense itching, which accompanies the eruption, resulting in excoriations, scarring, and permanent hyperpigmentation were reported. Histopathological study revealed the characteristic features of Simulium bite reaction, such as vesicles filled with serous fluid, dermal edema, and perivascular infiltrates rich in eosinophils and lymphocytes.
The clinical manifestations and severity of Simulium dermatitis are serious matters of concern in hypersensitive persons.
在存在蚋类的地区，人及动物都会罹患皮肤性蚋皮炎，这是一种常见的问题。其特征为因对刺叮的蚋类或黑蝇产生过敏反应，而导致慢性出现瘙痒性丘疹、水疱和红斑性风团。在有刺叮人类的蚋类存在的地方，它可导致严重的皮肤并发症。
我们报告来自印度东北部的 2 例皮肤性蚋皮炎的临床病例。对其中 1 例进行了组织病理学研究，另 1 例则成功地用药物治疗。
报告了伴随出疹出现的剧烈瘙痒等临床特征，导致搔抓、结瘢和永久性色素沉着过度。组织病理学研究显示了蚋叮咬反应的特征性表现，如充满浆液的水疱、真皮水肿和富含嗜酸性粒细胞和淋巴细胞的血管周围浸润。
在过敏人群中，皮肤性蚋皮炎的临床表现和严重程度是严重关切的问题。
