Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Saitama, Japan.
J Stroke Cerebrovasc Dis. 2012 Nov;21(8):911.e5-8. doi: 10.1016/j.jstrokecerebrovasdis.2011.11.007. Epub 2011 Dec 17.
A 63-year-old man presented with aphasia. A computed tomographic scan of the head revealed hemorrhagic infarction in the left temporal lobe. Magnetic resonance venography (MRV) revealed no flow from the straight sinus and left transverse sinus to the sigmoid sinus, indicating cerebral venous sinus thrombosis (CVST). Because of rapidly deteriorating consciousness despite heparin infusion, neuroendovascular therapy was performed, recanalization was achieved, and the level of consciousness improved. In Western countries, neuroendovascular therapy is often aggressively performed in patients with worsening symptoms despite anticoagulation. However, in Japan, such reports are extremely rare. We recommend neuroendovascular therapy for deep CVST resistant to anticoagulant therapy.
一位 63 岁男性出现语言障碍。头部计算机断层扫描显示左颞叶出血性梗死。磁共振静脉造影(MRV)显示直窦和左侧横窦无血流进入乙状窦,提示脑静脉窦血栓形成(CVST)。尽管给予肝素输注,患者意识状态仍迅速恶化,因此进行了神经血管内治疗,实现再通,意识水平改善。在西方国家,尽管抗凝治疗后症状恶化,神经血管内治疗常积极进行。然而,在日本,此类报告极为罕见。我们建议对对抗凝治疗有抵抗的深部 CVST 进行神经血管内治疗。