细胞凋亡诱导与肿瘤细胞再增殖：放射治疗的阴阳两面 - Suppr

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超能文献

Apoptosis induction and tumor cell repopulation: the yin and yang of radiotherapy.

作者信息

Lauber Kirsten, Munoz Luis E, Berens Christian, Jendrossek Verena, Belka Claus, Herrmann Martin

机构信息

Department of Radiation Oncology, LMU Munich, Germany.

出版信息

Radiat Oncol. 2011 Dec 19;6:176. doi: 10.1186/1748-717X-6-176.

DOI:10.1186/1748-717X-6-176

PMID:22182804

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3264523/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57f4/3264523/deb6aa5ec4e2/1748-717X-6-176-1.jpg

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本文引用的文献

A downside to apoptosis in cancer therapy?

Nat Med. 2011 Jul 7;17(7):780-2. doi: 10.1038/nm0711-780.

Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy.半胱天冬酶 3 介导的癌症放射治疗期间肿瘤细胞再增殖。

Nat Med. 2011 Jul 3;17(7):860-6. doi: 10.1038/nm.2385.

Phase I/II trial of a COX-2 inhibitor with limited field radiation for intermediate prognosis patients who have locally advanced non-small-cell lung cancer: radiation therapy oncology group 0213.局限性野照射联合 COX-2 抑制剂的Ⅰ/Ⅱ期临床试验用于局部晚期非小细胞肺癌中具有中等预后的患者：放射肿瘤学组 0213。

Clin Lung Cancer. 2011 Mar;12(2):125-30. doi: 10.1016/j.cllc.2011.03.007. Epub 2011 Apr 11.

Targeting apoptosis pathways by Celecoxib in cancer.塞来昔布通过靶向细胞凋亡通路治疗癌症。

Cancer Lett. 2013 May 28;332(2):313-24. doi: 10.1016/j.canlet.2011.01.012. Epub 2011 Feb 22.

The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation.Akt 抑制剂依鲁替尼诱导前列腺癌细胞凋亡，并增强电离辐射的短期作用。

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AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis.AT-101，一种抗凋亡Bcl-2家族成员的小分子抑制剂，激活SAPK/JNK通路并增强辐射诱导的细胞凋亡。

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