Fesq G, Laporte J P, Mellat M, Piquet J, Bignon J
Clinique de Pathologie respiratoire, Centre hospitalier intercommunal de Créteil.
Rev Pneumol Clin. 1990;46(2):83-4.
The authors present 2 cases of mycoplasmal pneumonia associated with severe haemolysis. Haemolytic anaemia is a well-known and habitually mild complication of the disease. It is related to a peak of cold agglutinins, which are antibodies that agglutinate red blood cells usually at low temperatures but sometimes at 37 degrees C when they are present in high concentrations. The pathogenesis of cold agglutinins is thought to involve the secretion of peroxides by Mycoplasma pneumoniae with alteration of ed cell antigens which become immunogenic.
作者报告了2例与严重溶血相关的支原体肺炎病例。溶血性贫血是该疾病一种广为人知且通常较为轻微的并发症。它与冷凝集素峰值有关，冷凝集素是一种抗体，通常在低温下会使红细胞凝集，但当它们高浓度存在时，有时在37摄氏度也会使红细胞凝集。冷凝集素的发病机制被认为涉及肺炎支原体分泌过氧化物，导致红细胞抗原发生改变，从而变得具有免疫原性。
