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活性氧物质在收缩过程中调节骨骼肌葡萄糖摄取吗?

Do reactive oxygen species regulate skeletal muscle glucose uptake during contraction?

机构信息

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

出版信息

Exerc Sport Sci Rev. 2012 Apr;40(2):102-5. doi: 10.1097/JES.0b013e318245837b.

DOI:10.1097/JES.0b013e318245837b
PMID:22183040
Abstract

The mechanisms regulating skeletal muscle glucose uptake during contraction remain poorly defined. Recent studies suggest reactive oxygen species may be an important signaling intermediate for the regulation of skeletal muscle glucose uptake during ex vivo contraction but less important during more physiological conditions, such as in situ muscle contraction in rodents and during exercise in humans.

摘要

调控收缩时骨骼肌葡萄糖摄取的机制仍不清楚。最近的研究表明,活性氧可能是调节离体收缩时骨骼肌葡萄糖摄取的重要信号中间体,但在更生理的条件下,如啮齿动物的原位肌肉收缩和人类的运动时,其作用就不那么重要了。

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