Department of Pediatrics, University Hospital of North Norway, N-9038 Tromsø, Norway.
Pediatrics. 2012 Jan;129(1):e9-e16. doi: 10.1542/peds.2011-0248. Epub 2011 Dec 19.
The aim of this study was to examine the effectiveness of an early intervention program on behavioral outcomes at corrected age of 5 years for children with birth weights (BWs) of <2000 g.
A randomized controlled trial of a modified version of the Mother-Infant Transaction Program was performed. Outcomes were measured by the Child Behavior Check List report (parents) and Strengths and Difficulties Questionnaire at 5 years (parents and preschool teachers).
A total of 146 infants were assigned randomly (intervention group: 72 infants; reference group: 74 infants). A term group was recruited (75 infants). The mean BWs were 1396 ± 429 g for the intervention group, 1381 ± 436 g for the control group, and 3619 ± 490 g for the term reference group. Parents in the intervention group reported significantly fewer behavioral problems measured by both instruments at 5 years. There were no differences in behavior problems reported by preschool teachers. Significantly more children in the preterm control group scored within the clinical area of both instruments.
This modified version of the Mother-Infant Transaction Program led to fewer behavioral problems reported by parents at corrected age of 5 years for children with BWs of <2000 g.
本研究旨在探讨早期干预方案对出生体重（BW）<2000 克的儿童在矫正年龄 5 岁时的行为结果的有效性。
对母亲-婴儿互动程序的改良版本进行了随机对照试验。采用儿童行为检查表报告（家长）和 5 岁时的优势与困难问卷（家长和学前教师）来评估结果。
共有 146 名婴儿被随机分配（干预组：72 名婴儿；对照组：74 名婴儿）。还招募了一个足月组（75 名婴儿）。干预组的平均 BW 为 1396±429g，对照组为 1381±436g，足月对照组为 3619±490g。干预组的家长报告在 5 岁时，使用两种工具测量的行为问题明显较少。学前教师报告的行为问题没有差异。在早产对照组中，更多的儿童在两种工具的临床区域内得分。
对于 BW<2000 克的儿童，这种改良版的母亲-婴儿互动程序可减少家长在矫正年龄 5 岁时报告的行为问题。
