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[先天性弓形虫病的诊断问题]

[Diagnostic problems with congenital toxoplasmosis].

作者信息

Karczewski Grzegorz, Gołab Elzbieta

机构信息

Grupa Lux Med, Narodowego Instytutu Zdrowia Publicznego- Państwowego Zakładu Higieny w Warszawie.

出版信息

Przegl Epidemiol. 2011;65(3):451-4.

PMID:22184947
Abstract

Congenital toxoplasmosis results from the primary infection with Toxoplasma gondii during the pregnancy. The more advanced pregnancy the higher risk of foetus infection, however the symptoms might be mild or the infection can be asymptomatic. However, undiagnosed infection in a new born baby results in further development of the disease in early childhood reflecting in sight and hearing impairment, neurological symptoms or mental retardation. Systematic and frequent serologic tests performed during the pregnancy can lead to the early diagnosis of primary infection and help to implement the treatment which slows down the disease progression in children with intrauterine infection. It also reduces the costs of long-term medical care required for the significantly disabled patients.

摘要

先天性弓形虫病是由孕期初次感染弓形虫引起的。孕期越往后,胎儿感染的风险越高,不过症状可能较轻或感染可能无症状。然而,新生儿未被诊断出的感染会导致疾病在幼儿期进一步发展,表现为视力和听力障碍、神经症状或智力迟钝。孕期进行系统且频繁的血清学检测可实现原发性感染的早期诊断,并有助于实施治疗,减缓宫内感染患儿疾病的进展。这也降低了严重残疾患者所需的长期医疗护理成本。

相似文献

1
[Diagnostic problems with congenital toxoplasmosis].[先天性弓形虫病的诊断问题]
Przegl Epidemiol. 2011;65(3):451-4.
2
Management of Toxoplasma gondii infection during pregnancy.孕期弓形虫感染的管理
Clin Infect Dis. 2008 Aug 15;47(4):554-66. doi: 10.1086/590149.
3
[Congenital toxoplasmosis in own studies].[自身研究中的先天性弓形虫病]
Wiad Parazytol. 2001;47 Suppl 1:51-7.
4
[Congenital toxoplasmosis due to maternal reinfection during pregnancy].孕期母亲再次感染所致先天性弓形虫病
Arch Pediatr. 2011 Jul;18(7):761-3. doi: 10.1016/j.arcped.2011.04.011. Epub 2011 May 19.
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[Immune response and diagnostic aspects during Toxoplasma gondii infection].[弓形虫感染期间的免疫反应及诊断方面]
Wiad Parazytol. 2000;46(3):315-25.
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[Use of the ISAGA method in detection of specific IgM, IgA, IgE antibodies in acquired and congenital toxoplasmosis].[ISAGA方法在检测获得性和先天性弓形虫病特异性IgM、IgA、IgE抗体中的应用]
Wiad Parazytol. 1997;43(1):39-51.
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[Congenital toxoplasmosis: possibilities for laboratory diagnosis].[先天性弓形虫病:实验室诊断的可能性]
Epidemiol Mikrobiol Imunol. 2005 Apr;54(2):75-7.
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[Detection of congenital toxoplasmosis in utero with a polymerase chain reaction on amniotic fluid].[通过羊水聚合酶链反应检测子宫内先天性弓形虫病]
Wiad Parazytol. 2002;48(3):311-5.
9
[Toxoplasmosis diagnosis in pregnancy: computer assisted follow-up interpretation of serologic tests].
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Congenital toxoplasmosis.先天性弓形虫病
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Plasma microRNAs are promising novel biomarkers for the early detection of Toxoplasma gondii infection.血浆微小RNA是用于早期检测弓形虫感染的很有前景的新型生物标志物。
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