Ter Arkh. 2011;83(10):45-8.
Recently, much attention of medical professionals is directed to correlations between hyperuricemia, arterial hypertension, metabolic syndrome and renal affection because of the evidence that elevated blood level of uric acid raises the risk of cardiovascular complications not only in arterial hypertension and metabolic syndrome but also in diabetes mellitus type 2, coronary heart disease, congestive heart failure and renal dysfunction. Administration of uricosuric medication in hyperuricemia and goat has contraindications in some cases. A number of trials show a corrective action of lozartan. Other blockers of receptors to angiotensin II has no such effect.
最近，医学专业人士将大量注意力投向高尿酸血症、动脉高血压、代谢综合征和肾脏病变之间的关联，因为有证据表明，血尿酸水平升高不仅会增加动脉高血压和代谢综合征患者发生心血管并发症的风险，还会增加2型糖尿病、冠心病、充血性心力衰竭和肾功能不全患者的风险。在高尿酸血症中使用促尿酸排泄药物在某些情况下存在禁忌。多项试验表明氯沙坦具有纠正作用。其他血管紧张素II受体阻滞剂则没有这种效果。
