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Breast cancer: Increasing therapy options for HER2-positive early breast cancer.

作者信息

Harbeck Nadia

出版信息

Nat Rev Clin Oncol. 2011 Dec 21;9(1):10-2. doi: 10.1038/nrclinonc.2011.193.

DOI:10.1038/nrclinonc.2011.193
PMID:22186934
Abstract
摘要

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Updates in anti-HER2 combination therapy.抗HER2联合治疗的进展
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Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA).曲妥珠单抗联合帕妥珠单抗与标准新辅助含蒽环类和不含蒽环类化疗方案联合用于人表皮生长因子受体 2 阳性早期乳腺癌患者:一项随机 II 期心脏安全性研究(TRYPHAENA)。
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5
HER2/CEP17 ratio and HER2 immunohistochemistry predict clinical outcome after first-line trastuzumab plus taxane chemotherapy in patients with HER2 fluorescence in situ hybridization-positive metastatic breast cancer.HER2/CEP17 比值和 HER2 免疫组化预测 HER2 荧光原位杂交阳性转移性乳腺癌患者一线曲妥珠单抗联合紫杉烷化疗后的临床结局。
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Eur J Cancer. 2019 Nov;122:91-100. doi: 10.1016/j.ejca.2019.09.014. Epub 2019 Oct 18.
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Chin J Cancer Res. 2012 Jun;24(2):143-50. doi: 10.1007/s11670-012-0143-6.

本文引用的文献

1
Adjuvant trastuzumab in HER2-positive breast cancer.曲妥珠单抗辅助治疗 HER2 阳性乳腺癌。
N Engl J Med. 2011 Oct 6;365(14):1273-83. doi: 10.1056/NEJMoa0910383.
2
Adjuvant trastuzumab with chemotherapy is effective in women with small, node-negative, HER2-positive breast cancer.辅助曲妥珠单抗联合化疗对小的、淋巴结阴性、HER2 阳性乳腺癌女性有效。
Cancer. 2011 Dec 15;117(24):5461-8. doi: 10.1002/cncr.26171. Epub 2011 Jun 16.
3
Coping with uncertainty: T1a,bN0M0 HER2-positive breast cancer, do we have a treatment threshold?应对不确定性:T1a,bN0M0 HER2 阳性乳腺癌,我们有治疗阈值吗?
Ann Oncol. 2011 Nov;22(11):2387-2393. doi: 10.1093/annonc/mdq786. Epub 2011 Mar 15.
4
Cardiovascular complications of conventional and targeted adjuvant breast cancer therapy.常规和靶向辅助乳腺癌治疗的心血管并发症。
Ann Oncol. 2011 Jun;22(6):1250-1258. doi: 10.1093/annonc/mdq543. Epub 2010 Nov 26.
5
Effect of neoadjuvant anthracycline-taxane-based chemotherapy in different biological breast cancer phenotypes: overall results from the GeparTrio study.新辅助蒽环类药物联合紫杉类化疗在不同生物学乳腺癌表型中的疗效:GeparTrio 研究的总体结果。
Breast Cancer Res Treat. 2010 Nov;124(1):133-40. doi: 10.1007/s10549-010-1103-9. Epub 2010 Aug 10.
6
Topoisomerase II alpha as a marker predicting anthracyclines' activity in early breast cancer patients: ready for the primetime?拓扑异构酶IIα作为预测早期乳腺癌患者蒽环类药物活性的标志物:准备好进入黄金时代了吗?
Eur J Cancer. 2008 Dec;44(18):2791-8. doi: 10.1016/j.ejca.2008.09.014. Epub 2008 Nov 5.
7
HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials.人表皮生长因子受体2(HER2)状态与早期乳腺癌辅助性蒽环类药物的疗效:随机试验的汇总分析
J Natl Cancer Inst. 2008 Jan 2;100(1):14-20. doi: 10.1093/jnci/djm252. Epub 2007 Dec 25.
8
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer.曲妥珠单抗联合辅助化疗用于可手术的HER2阳性乳腺癌
N Engl J Med. 2005 Oct 20;353(16):1673-84. doi: 10.1056/NEJMoa052122.
9
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer.HER2阳性乳腺癌辅助化疗后使用曲妥珠单抗。
N Engl J Med. 2005 Oct 20;353(16):1659-72. doi: 10.1056/NEJMoa052306.