Goris Gbenou Maximilien C, Wahidy Tawfik, Llinares Karine, Cracco Dominique, Perrot Alain, Riquet Dominique
Department of Urology, Centre Hospitalierde Valence, Valence, France. mcgoris @ gmail.com
Case Rep Oncol. 2011 Sep;4(3):542-6. doi: 10.1159/000334747. Epub 2011 Nov 22.
Cutaneous metastases from colorectal cancer are uncommon, accounting for 6.5% of all secondary skin lesions. They occur in advanced disease. The most common site is the abdomen. The penis is a rare site.
We report the case of a 79-year-old patient who presented, two years after rectocolectomy for a rectal adenocarcinoma, obstructive renal failure secondary to a presacral recurrence, as well as symptomatic phimosis associated with papulonodules invading the penis, scrotum and pubis. After hemodialysis, percutaneous pyelostomy, and double-J catheter placement, the patient underwent circumcision and a pubic skin biopsy. On histology and immunohistochemistry, a cutaneous metastasis originating from the rectal adenocarcinoma was diagnosed.
Penile invasion by colorectal cancer revealed by phimosis is a rare occurrence but needs to be recognized and promptly diagnosed by biopsy in order to propose appropriate adjuvant therapy. These rare lesions can occur without any liver or lung involvement.
结直肠癌的皮肤转移并不常见,占所有继发性皮肤病变的6.5%。它们发生于晚期疾病。最常见的部位是腹部。阴茎是一个罕见的部位。
我们报告一例79岁患者,该患者在因直肠腺癌行直肠结肠切除术后两年出现骶前复发继发梗阻性肾衰竭,以及伴有丘疹结节侵犯阴茎、阴囊和耻骨的症状性包茎。在进行血液透析、经皮肾造瘘术和双J导管置入术后,患者接受了包皮环切术和耻骨皮肤活检。经组织学和免疫组织化学检查,诊断为源自直肠腺癌的皮肤转移。
包茎所揭示的结直肠癌侵犯阴茎是一种罕见情况,但需要通过活检予以识别并及时诊断,以便提出适当的辅助治疗。这些罕见病变可在无任何肝或肺受累的情况下发生。