Yuasa Uhito, Kogure Shuhei, Yamamoto Naoki, Watanabe Fumiaki, Tokui Toshiya, Shomura Sekira
Department of Chest Surgery, Yamada Red Cross Hospital, Ise, Japan.
Kyobu Geka. 2011 Nov;64(12):1114-7.
Myotomy or myectomy are well known as the standard treatment of hypertrophic obstructive cardiomyopathy (HOCM), and mitral valve replacement (MVR) is reported to achieve the equivalent therapeutic effect. And recently, combined treatment with artificial chordae replacement and MVR has been reported to improve the prognosis. We herein describe a case of a patient with HOCM who developed acute exacerbation of heart failure. The patient was 74-year-old woman, who had been followed by chronic atrial fibrillation (Af) and HOCM for 3 years. The findings at echocardiography included septal hypertrophy, systolic anterior motion (SAM) of the mitral valve, severe stenosis of left ventricular outflow tract (LVOT), and severe mitral valve regurgitation (MR). Calcification of mitral valve was also found. After the medical management, the patient was treated successfully by MVR using a mechanical valve combined with artificial chordae replacement. Maze procedure was also performed for chronic Af. The postoperative course was uneventful. MVR combined with artificial chordae replacement could be one of the useful strategies for HOCM associated with severe MR and organic changes of mitral valve.
肌切开术或肌切除术是肥厚性梗阻性心肌病(HOCM)的标准治疗方法,据报道二尖瓣置换术(MVR)可取得同等治疗效果。最近,有报道称人工腱索置换联合MVR的联合治疗可改善预后。我们在此描述一例HOCM患者发生心力衰竭急性加重的病例。该患者为一名74岁女性,患有慢性心房颤动(Af)和HOCM,病程已3年。超声心动图检查结果包括室间隔肥厚、二尖瓣收缩期前向运动(SAM)、左心室流出道(LVOT)严重狭窄以及严重二尖瓣反流(MR)。还发现二尖瓣钙化。经过药物治疗后,患者成功接受了使用机械瓣膜联合人工腱索置换的MVR治疗。同时还对慢性Af进行了迷宫手术。术后病程顺利。MVR联合人工腱索置换可能是治疗伴有严重MR和二尖瓣器质性改变的HOCM的有效策略之一。