Suppr超能文献

活体肺叶移植供者的结局和肺功能。

Outcomes and pulmonary function in living lobar lung transplant donors.

机构信息

Department of Thoracic Surgery, Kyoto University, Kyoto, Japan.

出版信息

Transpl Int. 2012 Feb;25(2):153-7. doi: 10.1111/j.1432-2277.2011.01401.x. Epub 2011 Dec 21.

Abstract

Successful living-donor lobar lung transplantation (LDLLT) largely depends on donor outcome; however, there are few studies that have assessed outcomes of LDLLT donors, particularly pulmonary function. We investigated the outcomes and pulmonary function after donor lobectomy in LDLLT donors. Retrospective evaluation of consecutive 33 LDLLT donors was performed. Preoperative characteristics and perioperative and postoperative variables were investigated. Evaluation of pulmonary function 3, 6 and 12 months after donor lobectomy was performed prospectively. All donors were well alive after donor lobectomies. Morbidity was found in five donors (15%). Postoperative complications consisted of re-accumulation of pleural effusion requiring readmission in three donors and prolonged air leakage in two donors. Sacrifice of pulmonary arteries was performed in 20 donors (61%) with 1.4 ± 0.6 branches. Forced vital capacity was 77.8 ± 6.1%, 84.8 ± 6.0% and 89.4 ± 6.6% of the preoperative value 3, 6 and 12 months after donor lobectomy, respectively. Forced expiratory volume in 1 s was 80.5 ± 7.8%, 85.6 ± 8.9% and 89.3 ± 8.7% of the preoperative value 3, 6, and 12 months postoperatively. Living-donor lobectomy was performed with low morbidity. Pulmonary function even after lobectomy was better preserved than expected.

摘要

成功的活体供肺叶移植(LDLLT)在很大程度上取决于供体的结果;然而,评估 LDLLT 供体结果的研究很少,特别是对肺功能的评估。我们研究了 LDLLT 供体肺叶切除术后的结果和肺功能。回顾性评估了连续 33 例 LDLLT 供体。研究了术前特征以及围手术期和术后变量。前瞻性评估了供体肺叶切除术后 3、6 和 12 个月的肺功能。所有供体在肺叶切除术后均存活良好。5 名供体(15%)出现了发病率。术后并发症包括 3 名供体需要再次入院的胸腔积液再积聚和 2 名供体的持续漏气。20 名供体(61%)进行了肺动脉牺牲,牺牲了 1.4±0.6 支。术后 3、6 和 12 个月,用力肺活量分别为术前值的 77.8±6.1%、84.8±6.0%和 89.4±6.6%。1 秒用力呼气量分别为术前值的 80.5±7.8%、85.6±8.9%和 89.3±8.7%。肺叶切除术的发病率较低,即使在肺叶切除术后,肺功能也能得到较好的保留。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验