Gatineau Matthieu, Dupuis Jacques, Beauregard Guy, Charette Benoît, Breton Luc, Beauchamp Guy, d'Anjou Marc-André
Centre Vétérinaire DMV, Montréal (Lachine), Québec, Canada.
Vet Surg. 2012 Jan;41(1):42-53. doi: 10.1111/j.1532-950X.2011.00926.x. Epub 2011 Dec 20.
To determine the value of 2 diagnostic methods: (1) the reduction angle (RA) using the Ortolani maneuver and (2) the dorsal acetabular slope (DAS) from the dorsal acetabular rim (DAR) radiographic projection, to predict osteoarthritis (OA) in dogs with hip dysplasia.
Prospective study.
Dogs (n = 73).
Hip-extended ventrodorsal (VD) radiographic projections, RA, and DAS were evaluated when dogs were 6, 12, and 24 months of age. VD projections were qualitatively scored for OA. RA was determined using the Ortolani maneuver in dorsal recumbency and DAS using the DAR projection. Distraction index (DI) measurements from the compression-distraction radiographic projections (PennHIP method) were also performed at 6 months of age. Statistical analyses were used to establish the range of values of normal and abnormal RA and DAS, to document the temporal variation in RA and DAS, to compare the ability of the different methods to predict coxofemoral OA, to determine the influence of pure passive laxity and of the DAS on the occurrence of an Ortolani sign and on the magnitude of the RA, to establish the relationship between the DAS and subsequent development of passive laxity and coxofemoral OA, and to evaluate the influence of the DAS and RA on the occurrence of coxofemoral OA with severe, moderate, and minimal coxofemoral passive joint laxity, respectively.
VD, RA, DAS, and DI methods of coxofemoral joint evaluation correlated significantly with the status of the coxofemoral joints at 2 years of age. The risk of occurrence of coxofemoral OA increased, as the RA, DAS, or DI increased. There was a significant positive linear relationship between RA and DI (P = .015, r(2) = 0.32), RA and DAS (P = .0078, r(2) = 0.38), and DAS and DI (P = .015, r(2) = 0.33). A negative Ortolani sign was at all times significantly predictive of absence of coxofemoral OA at 2 years of age. DAS best predicted coxofemoral OA for DI ≥ 0.7, whereas RA best predicted coxofemoral OA for 0.3 < DI < 0.7; however, RA proved to be the best overall predictor of coxofemoral OA.
RA measured at 6 months of age in dorsal recumbency was the best predictor of coxofemoral OA at 2 years of age.
确定两种诊断方法的价值：（1）使用奥托尼拉尼手法的复位角度（RA）和（2）从髋臼背侧缘（DAR）X线投影测量的髋臼背侧倾斜度（DAS），以预测髋关节发育不良犬的骨关节炎（OA）。
前瞻性研究。
犬（n = 73）。
在犬6、12和24月龄时评估髋关节伸展前后位（VD）X线投影、RA和DAS。对VD投影进行OA的定性评分。采用仰卧位奥托尼拉尼手法测定RA，采用DAR投影测定DAS。在6月龄时还采用压迫-牵引X线投影（PennHIP法）进行牵引指数（DI）测量。采用统计分析确定正常和异常RA及DAS的值范围，记录RA和DAS随时间的变化，比较不同方法预测股髋关节炎的能力，确定单纯被动松弛和DAS对奥托尼拉尼征出现及RA大小的影响，建立DAS与随后被动松弛和股髋关节炎发展之间的关系，以及分别评估DAS和RA对严重、中度和轻度股髋被动关节松弛情况下股髋关节炎发生的影响。
股髋关节评估的VD、RA、DAS和DI方法与2岁时股髋关节状态显著相关。随着RA、DAS或DI升高，股髋OA发生风险增加。RA与DI（P = 0.015，r² = 0.32）、RA与DAS（P = 0.0078，r² = 0.38）以及DAS与DI（P = 0.015，r² = 0.33）之间存在显著正线性关系。阴性奥托尼拉尼征始终能显著预测2岁时无股髋OA。对于DI≥0.7，DAS最能预测股髋OA，而对于0.3 < DI < 0.7，RA最能预测股髋OA；然而，RA被证明是股髋OA总体上最佳的预测指标。
6月龄仰卧位测量的RA是2岁时股髋OA的最佳预测指标。
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