Hospital das Clínicas, Universidade de São Paulo, Nephrology Division, São Paulo, SP, Brazil.
Clinics (Sao Paulo). 2011;66(12):2151-7. doi: 10.1590/s1807-59322011001200023.
Ultrafiltration failure in patients undergoing peritoneal dialysis is a condition with an incidence that increases over time. It is related to increased cardiovascular morbidity and mortality and is a major cause of the abandonment of the treatment technique. Because the number of patients undergoing renal replacement therapy is increasing with society aging and because approximately 10% of this population is treated with peritoneal dialysis, this matter is becoming more common in everyday practice for clinicians involved in the care of patients with chronic renal failure. In this review, we summarize the available measures used to prevent and treat ultrafiltration failure and the current state of research in the field, both in the experimental and clinical settings, focusing on the possible clinical applications of recent findings.
超滤衰竭是腹膜透析患者的一种随时间推移发病率增加的病症。它与心血管发病率和死亡率的增加有关,也是导致治疗技术放弃的主要原因。由于随着社会老龄化接受肾脏替代治疗的患者数量不断增加,而且该人群中约有 10%接受腹膜透析治疗,因此对于参与慢性肾衰竭患者治疗的临床医生来说,这一问题在日常实践中变得越来越常见。在这篇综述中,我们总结了目前可用于预防和治疗超滤衰竭的措施,以及该领域的研究现状,重点关注最近发现的可能的临床应用。