Department of Neurology, Auckland City Hospital, Auckland, New Zealand.
J Neurol Neurosurg Psychiatry. 2012 May;83(5):543-50. doi: 10.1136/jnnp-2011-301162. Epub 2011 Dec 21.
Carotid endarterectomy (CEA) is an effective treatment for patients with recently symptomatic severe carotid stenosis and in selected patients with symptomatic moderate carotid stenosis. Carotid artery angioplasty and stenting (CAS) is emerging as an alternative to CEA, and randomised controlled trials suggest comparable efficacy to CEA in prevention of non-perioperative stroke. Neurovascular complications can result from both procedures, usually from thromboembolism from the operated vessel, cerebral hypoperfusion causing ischaemia and, rarely, intracerebral haemorrhage. The overall incidence of perioperative strokes complicating CEA and CAS is approximately 4% and 6%, respectively, and represents a devastating outcome that the procedure was designed to prevent. Other neurological sequelae complicating carotid revascularisation include cerebral hyperperfusion syndrome, cranial and peripheral nerve injuries, and contrast encephalopathy in patients undergoing CAS. In this review, we analyse the incidence, mechanisms and perioperative management of neurological complications for patients undergoing carotid revascularisation.
颈动脉内膜切除术 (CEA) 是治疗近期有症状的严重颈动脉狭窄患者的有效方法,对某些有症状的中度颈动脉狭窄患者也适用。颈动脉血管成形术和支架置入术 (CAS) 作为 CEA 的替代方法正在出现,随机对照试验表明其在预防非围手术期卒中方面与 CEA 疗效相当。这两种手术都可能导致神经血管并发症,通常是手术血管中的血栓栓塞、引起缺血的脑灌注不足,以及罕见的颅内出血。CEA 和 CAS 围手术期卒中并发症的总发生率分别约为 4%和 6%,这是手术旨在预防的灾难性后果。颈动脉血运重建术的其他神经并发症包括脑高灌注综合征、颅神经和周围神经损伤以及接受 CAS 的患者的对比性脑病。在这篇综述中,我们分析了接受颈动脉血运重建术的患者发生神经并发症的发生率、机制和围手术期管理。