经子宫切除术诊断为子宫腺肌病的临床特征：291 例回顾性研究。
Clinical characteristics indicating adenomyosis at the time of hysterectomy: a retrospective study in 291 patients.
机构信息
Department of Obstetrics and Gynecology, University Women's Clinic, Calwerstr. 7, 72076 Tuebingen, Germany.
出版信息
Arch Gynecol Obstet. 2012 Jun;285(6):1571-6. doi: 10.1007/s00404-011-2180-7. Epub 2011 Dec 23.
PURPOSE
To better characterize adenomyosis as a disease entity.
METHODS
We retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.
RESULTS
The study included 291 women: 38 with adenomyosis alone, 56 with adenomyosis and leiomyomas, and 197 with leiomyomas alone. In univariate analysis, women with adenomyosis were younger (p = 0.018) and had lower uterine weights (p < 0.001) and more disease-specific symptoms (p = 0.008). In multinomial logistic regression analysis, a lower uterine weight (OR 0.99, CI 95% 0.99-1.0), pelvic pain (OR 4.8, CI 95% 1.5-15.2), a history of smoking (OR 2.6, CI 95% 1.1-6.5) and at least one delivery (OR 4.3, CI 95% 1.5-12.3) were associated with a greater likelihood of having adenomyosis but not leiomyomas alone.
CONCLUSIONS
Women undergoing hysterectomy with adenomyosis alone have different clinical characteristics from women with adenomyosis and leiomyomas and from those with only leiomyomas.
目的
更好地将子宫腺肌病描述为一种疾病实体。
方法
我们回顾性分析了行子宫切除术且组织学诊断为单纯子宫腺肌病、子宫腺肌病伴肌瘤和单纯肌瘤的妇女的病历。
结果
该研究共纳入 291 名妇女：单纯子宫腺肌病 38 例，子宫腺肌病伴肌瘤 56 例，单纯肌瘤 197 例。单因素分析显示，子宫腺肌病患者年龄较小（p=0.018），子宫重量较低（p<0.001），且具有更多的疾病特异性症状（p=0.008）。在多变量逻辑回归分析中，较低的子宫重量（OR 0.99，95%CI 0.99-1.0）、盆腔疼痛（OR 4.8，95%CI 1.5-15.2）、吸烟史（OR 2.6，95%CI 1.1-6.5）和至少一次分娩（OR 4.3，95%CI 1.5-12.3）与发生子宫腺肌病而不是单纯肌瘤的可能性更大相关。
结论
行子宫切除术且单纯患有子宫腺肌病的妇女与同时患有子宫腺肌病和肌瘤以及单纯患有肌瘤的妇女具有不同的临床特征。
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