高级别胶质瘤中的治疗相关性变化与肿瘤复发：诊断难题——动态磁敏感对比增强（DSC）灌注 MRI 的应用。
Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI.
机构信息
Section of Neuroradiology, Department of Radiation Oncology, New York University School of Medicine, NYU Langone Medical Center, 550 First Ave, New York, NY 10016, USA.
出版信息
AJR Am J Roentgenol. 2012 Jan;198(1):19-26. doi: 10.2214/AJR.11.7417.
OBJECTIVE
The purpose of this article is to address radiation necrosis, pseudoprogression, and pseudoresponse relative to high-grade gliomas and evaluate the role of conventional MRI and, in particular, dynamic susceptibility contrast-enhanced perfusion MRI in assessing such treatment-related changes from tumor recurrence.
CONCLUSION
Posttreatment imaging assessment of high-grade gliomas remains challenging. Familiarity with the expected MR imaging appearances of treatment-related change and tumor recurrence will help distinguish these entities allowing appropriate management.
目的
本文旨在讨论高级别脑胶质瘤的放射性坏死、假性进展和假性缓解，并评估常规 MRI 的作用，特别是动态磁敏感对比增强灌注 MRI 在评估此类与治疗相关的肿瘤复发变化中的作用。
结论
高级别脑胶质瘤治疗后的影像学评估仍然具有挑战性。熟悉与治疗相关变化和肿瘤复发的预期 MRI 表现有助于区分这些病变，从而进行适当的治疗。
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