Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 601 N Caroline St, Baltimore, MD 21287, USA.
AJR Am J Roentgenol. 2012 Jan;198(1):162-72. doi: 10.2214/AJR.11.6505.
The purposes of this review are to describe the principles and method of MR spectroscopy, summarize current published data on musculoskeletal lesions, and report additional cases that have been analyzed with recently developed quantitative methods.
Proton MR spectroscopy can be used to identify key tissue metabolites and may serve as a useful adjunct to radiographic evaluation of musculoskeletal lesions. A pooled analysis of 122 musculoskeletal tumors revealed that a discrete choline peak has a sensitivity of 88% and specificity of 68% in the detection of malignancy. Modest improvements in diagnostic accuracy in 22 of 122 cases when absolute choline quantification was used encourage the pursuit of development of choline quantification methods.
本综述旨在描述磁共振波谱的原理和方法,总结当前发表的关于肌肉骨骼病变的资料,并报告使用最近开发的定量方法分析的其他病例。
质子磁共振波谱可用于识别关键的组织代谢物,并可能成为肌肉骨骼病变放射学评估的有用辅助手段。对 122 例肌肉骨骼肿瘤的汇总分析显示,离散的胆碱峰在检测恶性肿瘤时的敏感性为 88%,特异性为 68%。当使用绝对胆碱定量时,122 例中有 22 例的诊断准确性有适度提高,这鼓励人们寻求开发胆碱定量方法。