奥氮平相关的肌阵挛。
Olanzapine-associated myoclonus.
机构信息
Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA.
出版信息
Epilepsy Res. 2012 Feb;98(2-3):247-50. doi: 10.1016/j.eplepsyres.2011.07.020. Epub 2011 Dec 21.
Abstract
Olanzapine is an atypical antipsychotic drug that infrequently has been reported to cause seizures and myoclonus despite a small proconvulsant risk. This is the first report of generalized myoclonus induced in a patient who had been maintained on low dose olanzapine for over seven years without any change in her dose. Olanzapine was discontinued, and the myoclonic jerks completely resolved within 48 h.
摘要
奥氮平是一种非典型抗精神病药物，尽管有小的致惊厥风险，但很少有报道称其会引起癫痫发作和肌阵挛。这是首例报道的在一名患者中发生的全身性肌阵挛，该患者在低剂量奥氮平维持治疗超过 7 年，且剂量未发生变化。奥氮平停用后，肌阵挛性抽搐在 48 小时内完全缓解。
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