剂量依赖性奥氮平所致肌阵挛。
Dose-dependent olanzapine-induced myoclonus.
作者信息
Tikka Sai Krishna, Pratap Alok, Sinha Vinod Kumar
机构信息
Department of Psychiatry, K. S. Mani Center for Cognitive Neurosciences, Ranchi, Jharkhand, India.
Department of Psychiatry, Central Institute of Psychiatry, Ranchi, Jharkhand, India.
出版信息
Toxicol Int. 2014 Sep-Dec;21(3):335-6. doi: 10.4103/0971-6580.155393.
Abstract
Second-generation antipsychotics (SGA), mainly clozapine have been reported to induce myoclonus. Although olanzapine-induced myoclonus is reported, dose-dependent response has not been described. We report dose-related olanzapine-induced myoclonus in an early onset schizophrenia patient. We also suggest certain management strategies for such adverse side effects.
摘要
第二代抗精神病药物（SGA），主要是氯氮平，已被报道可诱发肌阵挛。虽然有奥氮平诱发肌阵挛的报道，但尚未描述其剂量依赖性反应。我们报告了一例早发性精神分裂症患者中与剂量相关的奥氮平诱发的肌阵挛。我们还针对此类不良反应提出了某些管理策略。
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