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[体外人脑肿瘤中谷氨酸和甘氨酸的积累]

[Accumulation of glutamic acid and glycine in human cerebral tumors in vitro].

作者信息

Zanchin G, Maggioni F, Gerosa M, Carteri A, Battistin L

出版信息

Riv Neurol. 1979 Mar-Apr;49(2):120-7.

PMID:221967
Abstract

Preliminary results are given on transport of glycine and L-glutamate into human cerebral tissue, normal and tumoral. In comparison with normal tissue, glycine transport is diminished in meningioma and oligodendroblastoma, unaffected in neurinoma, sharply increased in medulloblastoma. Glutamic acid transport is lowered in neurinoma and oligodendroblastoma; increased in medulloblastoma. Such preliminary observations are briefly discussed.

摘要

给出了甘氨酸和L-谷氨酸向正常及肿瘤性人类脑组织转运的初步结果。与正常组织相比,脑膜瘤和少突胶质细胞瘤中甘氨酸转运减少,神经鞘瘤中无影响,髓母细胞瘤中急剧增加。神经鞘瘤和少突胶质细胞瘤中谷氨酸转运降低;髓母细胞瘤中增加。对这些初步观察结果进行了简要讨论。

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