大脑中的垂体激素：位置、作用方式及原因？
Pituitary hormones in brain: where, how, and why?
作者信息
Krieger D T, Liotta A S
出版信息
Science. 1979 Jul 27;205(4404):366-72. doi: 10.1126/science.221983.
Peptide and protein hormones usually considered as being of pituitary origin have been detected within the central nervous system by means of radioimmunoassay, bioassay, and immunocytochemical techniques. Intracerebral administration of some of these hormones or fragments thereof elicit behavioral responses, suggesting that they may have a physiological role similar to that described for other peptidergic neurotransmitter or neuromodulator substances. Evidence available for some of these hormones indicates that they are synthesized within the central nervous system and that their regulation may differ from that of their pituitary counterparts.
通常被认为起源于垂体的肽类和蛋白质激素已通过放射免疫测定、生物测定和免疫细胞化学技术在中枢神经系统中被检测到。脑内给予其中一些激素或其片段会引发行为反应，这表明它们可能具有与其他肽能神经递质或神经调质物质所描述的类似的生理作用。关于其中一些激素的现有证据表明，它们是在中枢神经系统内合成的，并且其调节可能与其垂体对应物不同。
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