Kastin A J, Zadina J E, Banks W A, Graf M V
Peptides. 1984;5 Suppl 1:249-53. doi: 10.1016/0196-9781(84)90283-3.
Peptide research, like all of science, requires a careful balance between building upon previously accumulated knowledge and exploring perspectives that are in conflict with prevailing views. Many of the concepts discussed here originally stimulated certain lines of research. The downfall of most of these concepts, and thus their misleading nature, lies in the limitation of possible modes by which peptides are perceived to affect the functioning of the central nervous system (CNS).