Krawczyk W, Steć E
Ośrodka Dializ przy Oddziale Chorób Wewnetrznych.
Wiad Lek. 1990 Jun 1;43(11):501-5.
In 10 patients on chronic haemodialysis treatment for terminal renal failure with hypertension urapidil (Ebrantil) was given in one daily dose of 30 mg, usually continuing the previously used antihypertensive drugs. A significant decrease of the systolic and diastolic arterial blood pressure was achieved in most cases. Full therapeutic effect was manifested after several weeks of drug administration. During the treatment no tendency was noted for orthostatic hypotension, and no other side effects were observed. It seems that urapidil may be useful in the treatment of hypertension in dialysed patients. The usefulness of the drug in monotherapy requires further studies.
对于10例因终末期肾衰竭接受慢性血液透析治疗且患有高血压的患者,给予乌拉地尔(压宁定),每日剂量30毫克,通常继续使用先前使用的抗高血压药物。在大多数情况下,收缩压和舒张压均显著下降。给药几周后显现出完全的治疗效果。治疗期间未发现体位性低血压倾向,也未观察到其他副作用。乌拉地尔似乎可用于治疗透析患者的高血压。该药物单药治疗的有效性需要进一步研究。