[Relationship of acute urinary retention, bladder ischemia and metabolic changes in bladder wall and urine during infravesical obstruction due to benign prostatic hyperplasia].

Decrease of enzyme activity in the bladder wall in combination with increase of enzyme activity in the urine, affirm that exactly the bladder is the source of enzymuria increase and it is related with marked damage. Taking into consideration, that from the bladder wall not only cytoplazmatic enzymes come out but also enzymes connected with cell membranes, it is expected that high enzymuria is not only because of increase permeability of cytoplazmatic membrane for large molecules but also is connected with cell parts distruction. Similarity of changes during acute urinary retention and bladder wall ischemia let us assume vital value of the factor of changes of bladder wall blood supply during acute urinary retention and its role in the development of metabolic and functional changes.