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女性接受抗雌激素疗法治疗乳腺癌的经历。

Women's experiences with antiestrogen therapy to treat breast cancer.

作者信息

Flanagan Jane, Winters Loren N, Habin Karleen, Cashavelly Barbara

机构信息

Connell School of Nursing, Boston College, Massachusetts, USA.

出版信息

Oncol Nurs Forum. 2012 Jan;39(1):70-7. doi: 10.1188/12.ONF.70-77.

DOI:10.1188/12.ONF.70-77
PMID:22201657
Abstract

PURPOSE/OBJECTIVES: To understand the experiences of women undergoing antiestrogen therapy (AET) to treat breast cancer.

RESEARCH APPROACH

Content analysis of tape-recorded focus group interviews.

SETTING

Breast oncology center of a large medical center in the northeastern United States.

PARTICIPANTS

Purposive sample of 21 women undergoing AET to treat breast cancer.

METHODOLOGIC APPROACH

A nonexperimental qualitative, descriptive design using open-ended interviews and content analysis to isolate themes.

MAIN RESEARCH VARIABLES

Women's experiences with AET.

FINDINGS

Five themes were isolated and were focused on the overall experience of having breast cancer: symptoms related to AET, shared decision making, being strong for others, discovering new priorities, and recognizing vulnerability.

CONCLUSIONS

Oral therapies are an increasingly popular treatment option for various types of cancer, particularly in women with estrogen-sensitive breast cancer. Although this type of treatment has been efficacious in terms of disease-free and overall survival, women undergoing AET face many challenges related to treatment. Healthcare providers need to understand women's perceptions of AET and its effects as a first step in the process of developing interventions to improve care.

INTERPRETATION

More research is needed to distinguish whether the presence of preexisting chronic illness, differences in type of AET, age, and ethnicity impact the overall experience of women on AET. Individual interviews may be necessary to fully explore the experience. Oncology nurses should implement surveillance care to explore the effects of AET on women with breast cancer.

摘要

目的/目标:了解接受抗雌激素治疗(AET)以治疗乳腺癌的女性的经历。

研究方法

对录音的焦点小组访谈进行内容分析。

研究地点

美国东北部一家大型医疗中心的乳腺肿瘤中心。

参与者

21名接受AET治疗乳腺癌的女性的目的性样本。

方法学方法

采用非实验性定性描述性设计,通过开放式访谈和内容分析来提炼主题。

主要研究变量

女性接受AET的经历。

研究结果

提炼出五个主题,聚焦于患乳腺癌的总体经历:与AET相关的症状、共同决策、为他人保持坚强、发现新的优先事项以及认识到自身的脆弱性。

结论

口服疗法是治疗各类癌症越来越常用的治疗选择,尤其是对雌激素敏感的乳腺癌女性。尽管这类治疗在无病生存期和总生存期方面已显示出疗效,但接受AET的女性面临许多与治疗相关的挑战。医疗保健提供者需要了解女性对AET及其影响的看法,这是制定改善护理干预措施过程中的第一步。

解读

需要更多研究来区分是否存在预先存在的慢性病、AET类型差异、年龄和种族是否会影响接受AET女性的总体经历。可能需要进行个体访谈以充分探究这种经历。肿瘤护理人员应实施监测护理,以探究AET对乳腺癌女性的影响。

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