Seitzer D, Musch E, Kuhn W
Frauenklinik und Hebammenlehranstalt der Georg-August-Universität, Göttingen.
Zentralbl Gynakol. 1990;112(12):757-65.
Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%. Pleural effusions usually occur at a stage of the disease where no further curative therapeutic options exist. Therefore, the treatment should be effective and have a low side effect profile. The intrapleural administration of mitoxantrone in comparison with other pleurodesis techniques has been demonstrated to meet these requirements.
胸腔积液是妇科恶性疾病的常见并发症，尤其是在乳腺癌中，发生率约为50%。胸腔积液通常发生在疾病的某个阶段，此时已没有进一步的根治性治疗选择。因此，治疗应有效且副作用小。与其他胸膜固定术技术相比，米托蒽醌胸腔内给药已被证明符合这些要求。
