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多形核酵母细胞吞噬作用的补体依赖性:人与各种家畜之间的比较。

Complement-dependence of polymorphonuclear yeast cell phagocytosis: a comparison between man and various domestic animals.

作者信息

Reifenberg K, Stahl M, Lösch U

机构信息

Institut für Physiologie, Tierärztlichen Fakultät, Universität München.

出版信息

Zentralbl Veterinarmed B. 1990 Oct;37(8):561-9. doi: 10.1111/j.1439-0450.1990.tb01097.x.

Abstract

The complement-dependence of polymorphonuclear yeast cell phagocytosis of sheep, goat, cattle, horse, dog, pig and man is determined by comparing the opsonizing abilities of untreated sera with complement-inactivated autologous sera at a serum concentration of 2.5% and at different phagocytosis periods. The performed phagocytosis assays only detects incorporated particles and allows for the differentiation of granulocytes with different quantities of phagocytosed particles. In sheep, horse and man the addition of heat-inactivated serum reduces the phagocytosis index to less than -80% of the value obtained at untreated serum addition at a phagocytosis period of 60 min. The other species show a smaller reduction ranging from -66.9% (dog) to 41.4% (cattle). The evaluation of the distribution pattern of granulocytes incorporating a certain number of yeasts offers significant differences in the investigated species.

摘要

通过比较2.5%血清浓度下未处理血清与补体灭活的自体血清在不同吞噬期的调理能力,来确定多形核酵母细胞对绵羊、山羊、牛、马、狗、猪和人的吞噬作用的补体依赖性。所进行的吞噬试验仅检测摄入的颗粒,并能够区分吞噬了不同数量颗粒的粒细胞。在绵羊、马和人中,添加热灭活血清会使吞噬指数降低至低于在吞噬期60分钟时添加未处理血清所获得值的80%。其他物种的降低幅度较小,从-66.9%(狗)到41.4%(牛)不等。对摄入一定数量酵母的粒细胞分布模式的评估在被研究物种中显示出显著差异。

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