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[化疗放疗联合S-1治疗肛管鳞状细胞癌的病例报告]

[A case report of chemoradiotherapy combined with S-1 responding to squamous cell carcinoma of the anal canal].

作者信息

Baba Hironobu, Kuwabara Hiroshi, Wakabayashi Mai, Nakamura Hiroshi, Sanada Takahiro, Baba Hiroyuki, Nakajima Kazumi, Goseki Narihide

机构信息

Dept. of Surgery, Shuwa General Hospital.

出版信息

Gan To Kagaku Ryoho. 2011 Nov;38(12):2280-2.

Abstract

A 79-year-old woman was reffered to our hospital with the chief complaint of hematochezia. Type-2 tumor was found on anal canal by colonoscopy, and pathologic examination revealed a poorly differentiated squamous cell carcinoma. Computed tomography of the abdomen demonstrated obturatory node metastasis. The patient was diagnosed as having squamous cell carcinoma of the anal cana (l cStage III). After four months from chemoradiation (66 Gy/33 Fr plus S-1), the ulcer side was improved completely to epithelization, and abdominal CT scan showed a remarkable reduction of obturatory node metastasis. She was obtained a complete response. Now the patient is disease-free for ten months after chemoradiation.

摘要

一名79岁女性因便血为主诉转诊至我院。结肠镜检查发现肛管有2型肿瘤,病理检查显示为低分化鳞状细胞癌。腹部计算机断层扫描显示闭孔淋巴结转移。该患者被诊断为肛管鳞状细胞癌(l c期III期)。放化疗(66 Gy/33次分割加S-1)四个月后,溃疡面完全愈合上皮化,腹部CT扫描显示闭孔淋巴结转移明显减少。她获得了完全缓解。目前该患者在放化疗后已无病生存十个月。

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