Aoyama Toru, Yoshikawa Takaki, Hayashi Tsutomu, Kuwabara Hiroshi, Mikayama Yo, Ogata Takashi, Cho Haruhiko, Tsuburaya Akira, Rino Yasushi, Masuda Munetaka
Dept. of Gastrointestinal Surgery, Kanagawa Cancer Center.
Gan To Kagaku Ryoho. 2011 Nov;38(12):2331-3.
Survival and clinical course were unknown in patients with recurrence of para-aortic lymph node after curative D2 gastrectomy and adjuvant S-1 chemotherapy.
The study examined clinical characteristics and prognosis of 3 patients who had para-aortic nodal recurrence after curative D2 gastrectomy and S-1 adjuvant chemotherapy.
Initial stage was III C in all of the patients. Median treatment interval of S-1 was 8 . 8 months. Para-aortic nodal metastasis was single in 2 and multiple in 1 patient. Median survival time was 14 .3 months. Other recurrent sites than para- aortic node were not seen in all of the patients.
In the times of S-1 adjuvant chemotherapy, it is valuable to know whether para-aortic node should be resected prophylactically, or be treated after recurrence, or be treated by locally or systemically.
在接受根治性D2胃切除术及辅助性S-1化疗后出现主动脉旁淋巴结复发的患者中，其生存情况及临床病程尚不清楚。
本研究调查了3例在接受根治性D2胃切除术及S-1辅助化疗后出现主动脉旁淋巴结复发患者的临床特征及预后。
所有患者的初始分期均为IIIC期。S-1的中位治疗间隔时间为8.8个月。2例患者的主动脉旁淋巴结转移为单个，1例为多个。中位生存时间为14.3个月。所有患者均未出现除主动脉旁淋巴结以外的其他复发部位。
在使用S-1辅助化疗的时代，了解主动脉旁淋巴结是应预防性切除、复发后治疗还是进行局部或全身治疗具有重要价值。
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