Katsuta Eriko, Kaneko Jun, Iwata Noriko, Aoyagi Haruhiko, Yoshida Tsuyoshi, Takahata Taro, Hasegawa Kumi, Maejima Shizuaki
Dept. of Surgery, Hasuda Hospital.
Gan To Kagaku Ryoho. 2011 Nov;38(12):2334-5.
A 59-year-old man visited our department with the complaint of an abdominal mass. After detailed examination, he was diagnosed with cT3 (SE) N2M0, cStage III C gastric cancer and underwent a 3 course preoperative S-1/CDDP combination chemotherapy. After tumor down-staging was achieved after the 3 course combination chemotherapy, a surgery was scheduled. The patient underwent distal gastrectomy with D2 lymph node dissection. Histopathological diagnosis was M, type 1, 75 × 35 mm, papillary>moderately-differentiated tubular adenocarcinoma [pT2 (MP), ly3, v0, pN2, Stage IIB]. The patient is now treated with oral S-1 as postoperative adjuvant chemotherapy on an outpatient basis, and there are no signs of recurrence as of 1 year after the surgery. Preoperative chemotherapy appears to be a promising treatment option for gastric cancer with extensive lymph node metastasis.
一名59岁男性因腹部肿块主诉前来我院就诊。经过详细检查，他被诊断为cT3（SE）N2M0，c期IIIC型胃癌，并接受了3个疗程的术前S-1/顺铂联合化疗。在3个疗程的联合化疗后实现肿瘤降期后，安排了手术。患者接受了D2淋巴结清扫的远端胃切除术。组织病理学诊断为M，1型，75×35mm，乳头状>中度分化管状腺癌[pT2（MP），ly3，v0，pN2，IIB期]。该患者目前作为门诊患者接受口服S-1作为术后辅助化疗，术后1年无复发迹象。术前化疗似乎是治疗伴有广泛淋巴结转移的胃癌的一种有前景的治疗选择。
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