Kittaka Hirotada, Yamada Terumasa, Goto Kunihito, Ogawa Hisataka, Shingai Tatsushi, Motoori Masaaki, Takahashi Hidenori, Kishi Kentaro, Noura Shingo, Miyashiro Isao, Ohue Masayuki, Ohigashi Hiroaki, Yano Masahiko, Ishikawa Osamu
Dept. of Gastrointestinal Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases.
Gan To Kagaku Ryoho. 2011 Nov;38(12):2508-10.
We report a case of hepatic metastasis from gastric gastrointestinal stromal tumor (GIST), which was safely resected with preoperative imatinib therapy. A 60-year-old woman was hospitalized and underwent a treatment for hepatic SOL at another hospital prior to gastric GIST resection. Computed tomography revealed a tumor compressing the right and middle hepatic vein. The tumor volume decreased after an initiation of imatinib therapy aimed at preserving the middle hepatic vein. Although tumor volume was further decreased over the course of twelve months, a new lesion appeared, suggesting a progressive disease. Our findings suggest that a radical resection of gastric GIST to preserve the middle hepatic vein is possible.
我们报告一例胃胃肠道间质瘤（GIST）肝转移病例，该病例经术前伊马替尼治疗后成功切除。一名60岁女性在胃GIST切除术前因肝脏实性占位在另一家医院住院并接受治疗。计算机断层扫描显示一个肿瘤压迫右肝静脉和肝中静脉。旨在保留肝中静脉的伊马替尼治疗开始后，肿瘤体积减小。尽管在十二个月的疗程中肿瘤体积进一步减小，但出现了一个新病灶，提示疾病进展。我们的研究结果表明，有可能对胃GIST进行根治性切除以保留肝中静脉。
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